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Öğe The Role of Nurses in Addressing Health Effects of Climate Change and Wildfires(TERMEDIA PUBLISHING HOUSE LTD, 2022) Baykara Mat, Seda TugbaThe present study reviews existing evidence regarding the role of nursing in responses to climate change and wildfires caused by climate change, with the aim of enhancing nurses’ awareness about these issues. A total of 21 studies published between 2014 to 2021 and written in English or Turkish were included in the review. Analysis focused on the role of nursing in lessening negative impacts from climate change and wildfires. There is evidence to suggest that nurses can significantly assist with the prevention and alleviation of the effects of climate change and wildfires. Based on these findings, it is recommended that nurses take an active role in reducing likely risks and responding effectively when needed. The importance of flexible and proactive health systems that can predict needs during emergencies is also highlighted. Nurses should lead the way in designing national and international policies on emergencies and disasters, making suggestions, and contributing to national emergency response plans, management of human resources, and the continuity of basic care services.Öğe The Relationship Between Suicide and Hopelessness in Young Adults Aged 18-30: A Systematic Review(KARE PUBL, 2022) Çalışkan, Behice Belkıs; Bat Tonkuş, Merve; Alagöz, EceObjectives: This review presents a number of studies that assessed the concept of hopelessness in individuals aged 18 to 30 with a history of suicidal ideation and suicide attempt. Methods: The Turkish Citation Index, TR Index, Turkish Psychiatric Index, Wiley Online Library, PubMed, and Science Direct databases were reviewed between January and February 2021, and 18 qualitative and quantitative studies pub lished between 2016 and 2020 were selected. The 27-item Preferred Reporting Items for Systematic Reviews and Meta Analyses Checklist was used to evaluate the reporting characteristics. Results: The findings of 18 articles were reviewed and presented. The search revealed no studies examining suicide and hopelessness in Türkiye. In all, 12 of the studies were descriptive, 2 were randomized controlled studies, 2 were ret rospective studies, 1 was a cohort study, 1 was an experimental study, and 1 was a cross-sectional observational study. The data indicated that a greater level of hopelessness was associated with suicidal thoughts and behaviors. Conclusion: Hopelessness is an important predictor of suicide. Greater knowledge and awareness of the complex risk factors for suicide can be used to provide the appropriate early treatment to promote hope, provide coping skills, and prevent suicidal behavior. Additional studies examining the important suicide risk factor of hopelessness in Türkiye are neededÖğe The Evaluation of Videos about Branched-Chain Amino Acids Supplements on YouTube (TM): A Multi-Approach Study(MDPI, 2022) Çonak, Özge; Günalan, Elif; Turhan, Saadet; Yıldırım Çavak, Betül; Kaya Çebioğlu, İrem;Branched-chain amino acids (BCAAs) are one of the most controversial ergogenic aids in terms of effectiveness and safety. This study aimed to evaluate the quality and reliability of BCAA supplements related to English videos on YouTube™ and to synthesize with the sentiment–emotion analysis of comments on videos. The content analysis of the information on videos was evaluated with the use of DISCERN, Journal of American Medical Association (JAMA) benchmark criteria, and Global Quality Score (GQS). In addition, word cloud and sentiment and emotional analysis of comments in videos were performed with the R package. As a result, the mean ± standard error values of DISCERN, JAMA, and GQS scores of all videos were 29.27 ± 1.97, 1.95 ± 0.12, and 2.13 ± 0.17, respectively. It was found that advertisement-free videos have a significantly higher DISCERN and GQS score than advertisement-included videos (p < 0.05). A moderately significant positive correlation was determined between DISCERN score of video content and the positive sentiment of video comments (rs: 0.400, p = 0.002). In conclusion, it was determined that BCAA related YouTube™ videos have mostly very poor quality in terms of content and that videos with higher quality may receive positive comments from viewers according to the DISCERN instrument.Öğe The Effect of Exercise and Posture Training Given to Mothers Who Have a Child With Cerebral Palsy on Mothers' Musculoskeletal Pain(TURKEY ASSOC PHYSIOTHERAPISTS, 2022) Tahran, Özge; Polen Altun, Gamze; Okudan, Begüm; Azim Rezaei, Derya; Yeldan, İpek[Abstract Not Available]Öğe Regulation of Endometrial NF-Kappa B Expression in Patients with PCOS Undergoing Total Embryo Freezing(IMR PRESS, 2022) Karakus, CemilBackground: To investigate Nuclear Factor kappa B (NF-?B) expression pattern in the endometrial samples taken on the day of egg collection in women with polycystic ovarian syndrome (PCOS)scheduled for total embryo freezing due to the risk of ovarian hyper stimulation syndrome (OHSS). Methods: Forty women with PCOS scheduled for total embryo freezing due to the risk of ovarian hyperstimulation syndrome were included in the study. Twenty-five infertile women who decided to freeze all of their embryos for any reason other than PCOS were utilized as the control group. Endometrial sampling was performed from all patients in both groups im mediately following the egg collection. Five fertile women with at least two children constituted the second control group. Endometrial sampling was performed from fertile patients during the mid-luteal phase. After immunohistochemical staining of endometrial samples with NF-?B/p65, the intensity of endometrial NF-?B/p65 expression was measured utilizing the H-score method. Results: NF-?B/p65 immunoreactivity was detected in both luminal and glandular endometrial cells from all samples. The mean H-score of endometrial NF ?B/p65 expression in the PCOS group was significantly increased compared to age and Body mass index (BMI) matched control group and fertile controls. NF-?B/p65 immunoreactivity of the control and fertile groups were found to be similar. There was no statistically significant difference in the mean H-score of endometrial NF-?B/p65 expression between the control and fertile groups. A positive and significant correlation was found between H-score values of NF-?B and E2 (estradiol), endometrial thickness, total oocyte count and total follicle stimulating hormone (rFSH) dose on human chorionic gonadotropin (hCG) day. Similarly, a strong positive correlation was found between serum testosterone, insulin levels, Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) values and NF-?B values. In addition to progesterone values on hCG day, no significant correlation was found between other parameters and NF-?B. Con clusions: Increased endometrial NF-?B/p65 expression may contribute to the diminished reproductive potential of women with PCOS undergoing total embryo freezing.Öğe Laparoscopic Ovarian Drilling Improve Endometrial Receptivity by Increasing Production of Endometrial Metabolites(Cordus, 2022) Karakuş, CemilObjective: Laparoscopic ovarian drilling normalizes ovulation by reducing cortical thickening, lowering androgen production, and regulating luteinizing hormone pulse frequency. On the other hand, the effect of laparoscopic ovarian drilling on the endo metrium is unknown. This study was planned to investigate the changes in the functional markers of choline, creatine, lac tate, and lipid metabolites of the endometrium before and after laparoscopic ovarian drilling in women with polycystic ovary syndrome. Methods: Twenty women diagnosed with clomiphene-resistant polycystic ovary syndrome who did not ovulate successfully despite the administration of clomiphene citrate or aromatase inhibitor were included in the study. Patients were offered Assisted Reproductive Technology (ART) or laparoscopic ovarian drilling options. Patients who accepted laparoscopic ovarian drilling formed the study group. Endometrial MR spectroscopy was applied to the participants in the mid-luteal phase before laparoscopic ovarian drilling. Choline, creatine, lactate, and lipid metabolites of all patients were measured and denominated parts per million. The second MR spectroscopy was performed 2 months after the first MR spectroscopy, and the changes in endometrial metabolites after laparoscopic ovarian drilling were recorded. Twenty patients who did not have clinical and labo ratory findings of polycystic ovary syndrome and were matched for age and body mass index were accepted as the control group. The patients in this group were selected from fertile women with at least 2 children. MR spectroscopy was performed in the mid-luteal phase in fertile women. The obtained results were compared within and between groups and the possible effects of laparoscopic ovarian drilling on metabolite synthesis were tried to be determined. Results: During MR spectroscopy examination main endometrial metabolites choline, creatine, lactate, and lipid were detected in the polycystic ovary syndrome group. The most prominent metabolite peak before and after laparoscopic ovarian drilling was recorded as choline and creatine. There was a significant increase in choline and creatine peaks after laparoscopic ovarian drilling compared to the values before laparoscopic ovarian drilling. There was no significant increase in lactate and lipid signals before and after laparoscopic ovarian drilling. The choline and creatine metabolite levels of the women with polycystic ovary syndrome before laparoscopic ovarian drilling were significantly lower than those of the fertile women. The choline and creatine metabolite levels of the women with polycystic ovary syndrome after m laparoscopic ovarian drilling were similar to those of the fertile women. There was no significant difference between lactate and lipid signals before and after laparoscopic ovarian drilling. Conclusion: Laparoscopic ovarian drilling improves polycystic ovary syndrome-related subfertility by increasing endometrial choline and creatine metabolite levels to those of fertile women.Öğe Follicular Fluid 25-Hydroxyvitamin D Levels Determine Fertility Outcome in Patients with Polycystic Ovary Syndrome(ELSEVIER TAIWAN, 2022) Karakuş, Cemil; Özyurt, RamazanObjective: To determine the possible relationship between follicular fluid 25-hydroxyvitamin D [25(OH) D] levels and fertility outcome of women who underwent IVF/ICSI with the diagnosis of lean polycystic ovary syndrome. Materials and methods: Thirty patients who were diagnosed with PCOS according to the Rotterdam criteria and decided on IVF/ICSI were included in the study. Thirty patients who were scheduled for IVF/ ICSI for reasons other than PCOS and matched in terms of age and BMI were taken as the control group (non-PCOS). According to BMI values, patients in both PCOS and non-PCOS groups were lean. Women in both groups were aged 21e35 years with a normal BMI (18.5e24.9 kg/m2) and first IVF/ICSI attempt. Both groups of patients were followed up using the antagonist protocol. Vit D levels were measured in serum and follicular fluid (FF) samples taken on the day of oocyte collection. The correlation between FF vit D levels, the number of total oocytes, MII oocytes and 2 PN zygotes, HOMA-IR, hormonal and de mographic parameters, clinical pregnancy rate (CPR), live birth rate (LBR), and miscarriage rate were evaluated. Results: At the time of oocyte retrieval women with PCOS had similar serum Vitamin D compared to non PCOS women (21.8 (12.6e24.8) ng/ml vs 22.3 (11.5e25.1) ng/ml, p < 0.54). In FF, assessed on the day of oocyte retrieval, the concentration of Vitamin D was similar in women with PCOS when compared to non-PCOS women (11.2 (9.2e14.4) ng/ml vs 13.3 (11.1e17.4) ng/ml, p < 0.06). For both groups, Vitamin D levels were lower in FF compared to serum vit D. A positive correlation was found between serum and FF Vitamin D concentrations in the full cohort. A positive and significant correlation was found between FF vit D levels and the number of total oocyte (r ¼ 0.344, p < 0.04) and MII oocyte (r ¼ 0.404, p < 0.02) in the PCOS group. The number of total oocyte, MII oocyte and 2 PN zygotes of the PCOS group were signifi cantly higher than the non-PCOS group. Positive pregnancy test rate, clinical pregnancy and live birth rates were similar in both groups. The miscarriage rates in the non-PCOS group were significantly higher than in the PCOS group. A positive and significant correlation was also found between FF vit D levels and positive pregnancy test (r ¼ 0.566, p < 0.03) and CPR (r ¼ 0.605, p < 0.02) in PCOS group. There was no correlation between FF-vit D levels and live birth and miscarriage rates in neither the PCOS nor the non PCOS group. Conclusions: Both serum and FF 25-hydroxyvitamin D level of women with PCOS at the time of oocyte retrieval are similar to non-PCOS controls. While FF 25-hydroxyvitamin D levels correlate with total and MII oocyte counts, positive pregnancy test and CPR, it does not correlate with miscarriage and live birth rates.Öğe Evaluation of Hemoglobin and Hematocrit Values by the CO-Oximetry and Cyanide-Free Sodium Lauryl Sulphate Methods: A Retrospective Study(GALENOS PUBL HOUSE, 2022) Hocaoğlu, Fatma Sinem; Serin, Huriye; Oğuz, OsmanIntroduction: Blood gas analyzers (BGA) have recently been widely used as a rapid testing devices for the determination of hemoglobin (Hb) in the intensive care units and emergency services of hospitals. We compared the Hb and calculated hematocrit (Hct) values by the CO-oximetry and cyanide-free sodium lauryl sulphate (SLS) methods. Methods: Between January and June 2019, 12,049 patients who applied to the emergency department of İstanbul Training and research Hospital, for whole blood count and venous blood gas analysis were included. Samples were analyzed using SLS- Hb and CO-oximetry methods. Bland-Altman plot and Passing-Bablok regression analysis were performed to evaluate the accordance of the methods. Results: The correlation coefficients of the methods for Hb and Hct were 0.89 and 0.87, respectively (p<0.0001). Passing Bablok regression analysis showed a significant deviation from linearity (p<0.01). Bland-Altman plot showed insufficient agreement between of the two methods for each variable. Bias % calculated as 2.5% for Hb, and 1.1% for Hct. Total error calculated as 4.08% for Hb. Total error of CO-oximetric Hb value was within the limits of allowable total error. Conclusion: Although each test shows a significant deviation from linearity, BGA’s could be used for Hb measurements since the bias and total error were still acceptable.Öğe Effects of Topical Oils on Neonatal Skin: A Systematic Review(Lippincott Williams and Wilkins, 2022) Aksucu, Gözde; Azak, Merve; Çağlar, SedaOBJECTIVE: To identify studies that aimed to determine the effects of topical oils on neonatal skin. DATA SOURCES: Authors searched PubMed, Cochrane Central Register of Controlled Trials, and Science Direct databases. STUDY SELECTION: The databases were searched for studies published through February 2022 (when the search was conducted) using the keywords “skin”, “neonatal”, “infant”, and “oil”. Fourteen randomized controlled trials that met the eligibility criteria were included in the review. DATA EXTRACTION: Researchers used the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) reporting guidelines to guide this systematic review. Two authors reviewed and evaluated the articles independently. DATA SYNTHESIS: The 14 studies included in this review were conducted with a total of 5,683 neonates, most of whom were preterm. The included studies used blended sunflower (n = 8), coconut (n = 5), almond (n = 2), olive (n = 1), mustard (n = 1), and vegetable (n = 1) oils. These studies investigated the effects of topical oils on the skin’s barrier functions and skin integrity. Most studies used noninvasive measurement devices to evaluate the skin’s barrier functions; they used a variety of scoring systems to evaluate skin integrity. Eleven of the studies concluded that the oils used in the skincare of neonates effectively improve the skin condition and barrier functions of the skin. However, three studies found equivocal, negative, or mixed findings. CONCLUSION: Although current evidence indicates a potential benefit, more studies with a high level of evidence on the subject are required.Öğe Effectiveness of haptic technology in teaching urinary catheterization skill: A randomized controlled study(ELSEVIER SCIENCE INC, 2022) Kızıl, HamiyetHaptic systems represent some of the highest levels of computer-based education technologies and enable students to learn on a higher level. The purpose of this article is to determine the effectiveness of using haptic technology in teaching urinary catheter application skill on levels of success and satisfaction about this skill. Urinary catheterization application skill was taught with the standard curriculum (demonstration on the model) to the control group, while it was taught with haptic-controlled computer-based simulation technol ogy to the experimental group. The Checklist for Teaching Urinary Catheterization Skills mean score of the students was 58.5 § 20.1 in the control group and 94.9 § 3.3 in the experimental group. The catheter applica tion skill scores and level of satisfaction about the teaching method were significantly different in favor of the experimental group (p < .001). It is recommended to popularize the use of haptic teaching technologies in nursing education.Öğe Demographic and clinical characteristics of inpatient stroke patients in Turkey(Turkish Society of Physical Medicine and Rehabilitation, 2022) Uçar, Demet; vd.Objectives: This study aims to assess the stroke rehabilitation facilities provided by university hospitals (UHs) and training and research hospitals (TRHs) and to evaluate the geographical disparities in stroke rehabilitation.Patients and methods: Between April 2013 and April 2014 a total of 1,529 stroke patients (817 males, 712 females; mean age: 61.7±14.0 years; range, 12 to 91 years) who were admitted to the physical medicine and rehabilitation clinics in 20 tertiary care centers were retrospectively analyzed. Demographic, regional and clinical characteristics, details of rehabilitation period, functional status, and complications were collected. Results: The median duration of stroke was five (range, 1 to 360) months. The ratio of the patients treated in the TRH in the Marmara region was 77%, but only 25% of the patients were living in the Marmara region. Duration of hospitalization was longer in the TRHs with a median of 28 days compared to those of UHs (median: 22 days) (p<0.0001). More than half of the patients (55%) were rehabilitated in the Marmara region. Time after stroke was the highest in the Southeast region with a median of 12 (range, 1 to 230) months and the lowest in the Aegean region with a median of four (range, 1 to 84) months. Conclusion: This study provides an insight into the situation of stroke rehabilitation settings and characteristics of stroke patients in Turkey. A standard method of patient evaluation and a registry system may provide data about the efficacy of stroke rehabilitation and may help to focus on the problems that hinder a better outcomeÖğe Correlation between high Choline metabolite signal in spectroscopy and sperm retrieval chance at micro-TESE(Verduci, 2022) Karakuş, Cemil; Özyurt, R.OBJECTIVE: To determine the re lationship between choline (Cho) signal intensi ty measured before micro-dissection testicular sperm extraction (micro-TESE) and sperm re trieval rates in mTESE in non-obstructive azo ospermia (NOA) patients. PATIENTS AND METHODS: A total of 20 pa tients who underwent testicular MR spectros copy were included in the study. Participants consisted of 10 patients diagnosed with NOA and 10 fertile cases with normal sperm counts. Both groups of participants underwent bilater al testis MR spectroscopy. Ten patients in the NOA group underwent mTESE after spectros copy. The signal intensities of Cho, creatine (Cr), lactate, and lipids were analyzed and com pared with the results of fertile control. Cho sig nal intensity detected before mTESE in the NOA group and sperm retrieval rates were compared. RESULTS: Sperm was found in 5 of 10 patients who underwent mTESE. No sperm was found in five NOA cases. The main metabolites detected in NOA cases with sperm in mTESE were Cho and Cr. Cho and Cr signals were found to be signifi cantly lower in NOA cases where no sperm could be found in mTESE. Cho and Cr signal intensities of the fertile group were similar to NOA patients with sperm in mTESE but were significantly high er than those with NOA without sperm. While the cut-off value of Cho was 1.24 ppm (AUC 0.665, p = 0.01 [95% CI: 0.722–1.00]) the cut-off value of Cr was 1.18 ppm (AUC 0.887, p = 0.02 [95% CI]): 0.620–1.00]) for positive sperm retrieval. CONCLUSIONS: Detection of high Cho metab olite in the spectra before TESE in NOA patients increases sperm retrieval rates in mTESEÖğe Evaluation of Upper Extremity Movement, Pain Intensity, and Respiratory Functions in Patients Who Received Thoracotomy Sparing the Serratus Anterior Muscle(European Journal of Therapeutics, 2022) Karaaslan, Yasemin; vd.Objective: To evaluate upper extremity movement, pain intensity, and respiratory functions in preoperative and postoperative periods in patients undergoing thoracotomy sparing the serratus anterior muscle (TSSAM). Methods: Forty-three patients (25 male and 18 female) were included in this prospective observational cohort type study. In the preoperative period and on postoperative days 1, 2, 3, and 5, ipsilateral shoulder range of motion was evaluated by a goniometer, pain intensity was evaluated by a visual analog scale (VAS), and respiratory functions were evaluated by spirometry. Results: When compared with preoperative values, shoulder flexion and abduction angle, forced expiratory volume in 1 second (FEV1), and functional vital capacity (FVC) decreased on postoperative day 1, while VAS significantly increased (P < .05). Shoulder flexion and abduction angle, FEV1, and FVC significantly increased and VAS significantly decreased on postoperative days 2, 3, and 5 compared to postoperative day 1 (P < .05). However, they could not reach preoperative values on postoperative day 5 (P < .05). On postoperative day 1, while there was a correlation between pain and flexion (r = ?0.438; P = .003) and abduction (r = ?0.503; P = .001) angles, no correlation was found between pain and FEV1 (r = ?0.189; P = .225) and FVC (r = 0.009; P = .953). There was no correlation between pain and flexion, abduction, FEV1, and FVC on postoperative days 2,3, and 5 (P > .05). Conclusions: Patients undergoing the TSSAM had less upper extremity range of motion and respiratory functions and more pain intensity in the early postoperative period than in the preoperative period. It was observed that pain and flexion and abduction angles were negatively correlated on postoperative day 1. In the postoperative period, they should be taken into account in the design/development of rehabilitation programs.Öğe Can Online Dietitian Be a Novel Trend of Post-Pandemic Era in Turkey?(ACIBADEM MEHMET ALİ AYDINLAR ÜNİVERSİTESİ, 2022) Çonak, Özge; Günalan, ElifPurpose: The aim of this study was to investigate weight management-related Google search trends in Turkey prompted by the pandemic. Methods: Keywords were “diet”, “dietitian”, “body mass index”, “exercise”, “calorie”, “weight gain”, “healthy nutrition”, “weight loss”, “fat burning”, “slimming”, “online diet” and “online dietitian”. Data collection and time series analysis were completed using the 4.1.0 version of the R Studio program and its gtrendsR, ggplot2, prophet, dplyr, forecast and ggforce packages. SPSS software version 17 was used for statistical analysis of keyword relative search volumes (RSVs) during the prepandemic, early pandemic and late pandemic periods. Results: The RSV of “dietitian” keyword was significantly higher in the late pandemic period than in the early pandemic period (p< 0.05). “Exercise” and “online diet” keywords had significantly higher RSVs in the early pandemic period than in the prepandemic period (p< 0.05). The search queries for “healthy nutrition” were significantly lower in the late pandemic period than in the prepandemic period (p< 0.05). According to the search volume for the previous 10 years, the predicted search trends of “body mass index”, “exercise”, “healthy nutrition”, “online diet” and “online dietitian” tended to increase depending on the seasonal search profile. Conclusion: A large increase in actual and predicted search queries of “online dietitian” can provide some cues about public tendencies in the postpandemic era in Turkey. Some guidelines, including web-based communication competencies in dietitian-patient relationships and follow-ups of the diet on the online platform, should be published for the postpandemic period by authorities.Öğe Evaluation of Individual Innovative Characteristics and Problem-Solving Skills of Students(Gaziosmanpaşa Eğitim ve Araştırma Hastanesi, 2022) Açıksöz, Semra; Şendir, Merdiye; Kızıl, Hamiyet; Yılmaz Coşkun, ElaPurpose: The purpose of this study is to evaluate the individual innovative characteristics and problem-solving skills of students who are studying in health sciences. Methods: This research is descriptive. A sample of 608 students who were at school at the time of collection of the study data and who agreed to participate in the survey were included. Three data collection methods were employed: 1) A socio-demographic questionnaire, 2) Individual Innovativeness Scale, 3) Problem Solving Inventory. Results: The individual innovativeness level score of the students participating in the study was 67.13 ± 8.19; and the problem-solving skill score was 89.82 ± 19.23. Conclusions: The students perceived their individual innovativeness level in the questionable category and perceived themselves as moderately competent in problem solving skills. The positive relationship between these two skills suggests that plans for the development of these skills in education should be made.Öğe Prevalence of Anemia and Iron Deficiency Anemia Among Elementary School Children in Turkey(Annals of Medical Research, 2021) Hocaoğlu Emre, Fatma Sinem; Oğuz, OsmanAim: The purpose of our study was to determine the rate of anemia and iron store status in Turkish elementary school children. Materials and Methods: We included 1296 children applied to pediatrics department of a large teaching hospital and evaluated the hemoglobin, iron, unsaturated iron binding capacity and ferritin levels. Results: The results showed that 9.88% of the children had anemia and 1.62% had iron-deficiency anemia. Despite the normal Hemoglobin (Hb) levels, the ratio of children with low ferritin levels was found to be 36.49%, suggesting that children with normal Hb levels might not be having adequate level of iron stored. The Hb levels were found to be significantly lower in the group of 6- and 7-year old children when compared to other ages. Conclusion: Being an elementary issue for normal growth and academic success in school, iron status should be closely monitored in school children. Additionally, different age groups have different needs for iron supplementation; therefore contemporary guidelines for the management of anemia in children should be established by authorities.Öğe Birinci Basamak Sağlık Hizmetlerinden Yararlananların Hemşirelik İmajına İlişkin Algıları Ve Etkileyen Faktörler(Anadolu Hemşirelik ve Sağlık Bilimleri Dergisi, 2021) Mat, Seda Tuğba Baykara; Baykal, ÜlküAmaç: Araştırma, birinci basamak sağlık hizmetinden yararlananların hemşirelik imajına ilişkin algılarını ve bu algıya etki eden faktörleri belirlemek amacıyla gerçekleştirilmiştir. Yöntem: Bu kesitsel araştırma, bir Aile Sağlığı Merkezi’ne kayıtlı bulunan, Nisan-Mayıs 2015 tarihlerinde ilgili merkeze başvurarak hizmet alan ve araştırmaya katılmaya gönüllü olan 1853 kişi ile yürütülmüştür. Araştırmada veri toplama aracı olarak bireylerin kişisel özelliklerini belirlemeye yönelik bilgi formu ve Hemşirelik İmajı Ölçeği kullanılmıştır. Hemşirelik imajı ölçeği ve üç alt boyutunun puanları üzerine etkisi olduğu belirlenen bağımsız değişkenlerin etkisini bir arada değerlendirmek için çoklu regresyon analizi (Backward yöntemi) yapılmıştır. Bulgular: Çalışmada katılımcıların ölçekten ve alt boyutlarından aldıkları puan ortalamalarının 65.32±7.39 şeklinde orta düzeyde olumlu olduğu saptanmıştır. Çoklu regresyon analizi sonucunda dört değişkenin (meslek, eğitim durumu, ekonomik durumu, cinsiyet) katılımcıların hemşirelik imajı ölçeği toplam puanına ait değişimi %14 oranında açıkladığı görülmüştür. Regresyon katsayılarının anlamlılığına ilişkin t testi sonuçlarına göre anlamlı düzeyde etkili bulunan değişkenlerin meslek, eğitim düzeyi (p<.001), ekonomik durum (p<.01), cinsiyet (p<.05) şeklinde sıralandığı görülmüştür. Sonuç: Çalışma sonucunda; toplumun hemşirelik imajına ilişkin algısının orta düzeyde olumlu olduğu, sosyo-ekonomik durum, Eğitim durumu ve yaş değişkenlerinin artmasından olumsuz yönde etkilendiği, bununla birlikte hastanede refakatçi kalma, hemşireden hizmet alma durumunun genel görünüm imajına ilişkin algıyı olumsuz yönde etkilerken, mesleki ve eğitsel nitelikler ve iletişim alt boyutlarında olumlu algıya neden olduğu sonucuna ulaşılmıştır.Öğe Effects Of Erythropoıetın Pretreatment On Lıver, Kıdney, Heart Tıssue In Pentylentetrazol-Induced Seızures; Evaluatıon In Terms Of Oxıdatıve Markers, Prolıdase And Sıalıc Acıd(İstanbul University Press, 2021) Kaptanoğlu, Ayşegül; Kaptan, Zülal; Dar, Kadriye Akgün; Kapucu, Ayşegül; Kaleler, İslim; Üzüm, GülayObjective: The effects of erythropoietin (EPO) which has been frequently studied as an anti-epileptic agent, on peripheral tissues have not been investigated. This study investigated the effects on malondialdehyde (MDA), advanced protein oxidation products (AOPP), superoxide dismutase (SOD), prolidase and sialic acid (SA) levels in the heart, kidney and liver tissues of EPO pretreatment in pentylenetetrazole (PTZ)-induced seizures. Materials and Method: Thirty three male adult rats were divided into three groups. A saline-injected control group, a 60 mg/kg PTZ-injected group to induce seizures and a 3000 IU/kg EPO-injected group 24 hours before seizures. After seizure severity and seizure latency were scored, the rats sacrificed, the tissues were immediately removed for biochemical analyses. Results: The PTZ-induced seizures increased MDA in kidney (p<0.01) and AOPP in liver (p<0.05) but didn’t alter these markers in heart tissue. In all three tissues, SOD didn’t change due to seizures. The SA levels increased in the heart (p<0.001), de creased in the kidney (p<0.001), and were unchanged in liver. Prolidase increased (p<0.05) only in kidney, and was unchanged in other tissues. EPO-pretreatment decreased seizure severity and increased seizure latency. It prevented the increase in MDA in the kidney (p<0.01) but increased AOPP (p<0.05) and decreased SOD (p<0.01) and further increased prolidase more than the seizures increased (p<0.01). EPO-pretreatment prevented the increase in AOPP in the liver (p<0.05) but was ineffective in PTZ-induced SA changes in the heart and kidney. Conclusion: We think that the increase in the heart SA level in seizures is an original finding and deserves investigation in the context of seizure-related cardiac arrhytmias. Also, despite the EPO’s anti-seizure effect, increased protein oxidaiton and prolidase, especially in the kidney, is an other important finding that needs further research.Öğe Biological Variation Of Glycated Albumin, Glucose And Albumin İn Healthy Turkish Subjects(De Gruyter [Commercial Publisher], 2021) Hocaoğlu Emre, Fatma Sinem; Mercan, Hilal; Oğuz, OsmanObjectives: Biological variation (BV) in laboratory tests can be defined as the variation in analyte concentration over time within and between individuals. Glycated albumin (GA) is a ketoamine which is used in the short-term monitoring of diabetes. The aim of this research was to determine BV of GA, glucose, and albumin under a well-designed and standardized protocol. Methods: Blood samples were collected weekly from 21 healthy subjects (10 males, 11 females) for four consecutive weeks. Samples were analyzed using enzymatic methods in duplicate. After subjected to outlier and normality tests, variables as the within-subject biologic coefficient of variation (CVI) and between-subject biologic coefficient of variation (CVG), the index of individuality (II), and reference change value (RCV) were calculated. Results: Analytical coefficient of variation (CVA) was 3.5, 1.78, and 2.9%, for GA, glucose and albumin, respectively. The estimates for CVI and CVG: GA: 4.1%, 6.3%; glucose: 3.8%, 4.8%; albumin: 3.5%, 4%. RCVs and IIs were: 15%, 0.60; 12%, 0.79; 13%, 0.9 for GA, glucose and albumin, respectively. Conclusions: The BV data of GA derived from this study might be applied to understand routine test results better and establish the quality standards for the analyte. KeywordsÖğe Tip 2 Diyabetli Hastaların Beslenme Alışkanlıkları, Diyet Kalitesi ve Yeme Davranışlarının Değerlendirilmesi(ADAMOR Toplum Araştırmaları Merkezi, 2021) Akman, Mehmet; Kaynarpunar, ElifDiyabet, Türkiye’de prevalansı oldukça yüksek olan, mortalite ve morbiditeyi arttıran kronik metabolik bir hastalıktır. Kan şekeri kontrolünün sağlanmasında ve diyabetin neden olabileceği komplikasyonların önlenmesinde doğru beslenme alışkanlıkları ve diyet kalitesinin yüksek olması çok önemlidir. Bu çalışma tip 2 diyabetli bireylerin beslenme alışkanlıkları, diyet kalitesi ve yeme davranışlarını belirlemek amacıyla yapılmıştır. Çalışmaya Tip 2 diyabet tanısı almış 202 birey katılmıştır. Bireylerin; demografik özellikleri, beslenme alışkanlıkları bir anket formu ile sorgulanmış, ağırlıkları ve boy uzunlukları ölçülmüş, 3 günlük besin tüketim kaydı alınmış ve Hollanda Yeme Davranışı Anketi (DEBQ) uygulanmıştır. Kadın bireylerin günlük ortalama 1522.4 ± 332.19 kkal., erkeklerin ise 1846.4 ± 373.22 kkal. aldığı hesaplanmıştır. Sağlıklı Yeme İndeksi puanı tüm bireylerde ortalama 63.77±10.93 bulunmuştur. Tüketilen besin çeşidi sayısı ortalaması açısından kadınlar ile erkekler arasında istatistiksel olarak önemli farklılık bulunmamaktadır (p<0,05). Kadınların kısıtlayıcı yeme skoru ortalaması ve duygusal yeme skoru ortalaması erkeklerin kısıtlayıcı yeme skoru ortalaması ve duygusal yeme skoru ortalamasından istatistiksel olarak anlamlı düzeyde fazladır (p<0.05). Diyabetli hastalarda glisemik kontrolün sağlanması, komplikasyonların önlenmesi için yeme bozuklukları ve beslenme alışkanlıkları düzeltilmelidir.
