Distribution of Penicillin G from the Aqueous Phase to the Organic Phase Using Amberlite LA-2 Extractant in Different Diluents

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dc.contributor.authorUslu, Hasan
dc.contributor.authorGunyeli, Seyhan
dc.contributor.authorIlbay, Zeynep
dc.contributor.authorKirbaslar, S. Ismail
dc.date.accessioned2024-03-13T10:35:15Z
dc.date.available2024-03-13T10:35:15Z
dc.date.issued2014
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractBenzyl penicillin, known as penicillin G (PG), is a beta-lactam antibiotic and also a weak monocarboxylic acid. The penicillin G extraction from aqueous solution by Amberlite LA-2 in different diluents, that is, octan-1-ol, nonan-1-ol, 3-methyl-1-butanol, ethyl ethanoate, propyl ethanoate, 4-methylpentan-2-one, octan-2-one, octane, and decane has been studied. According to experimental results, some thermodynamic parameters, such as distribution coefficients (K-D), loading factors (Z), and the extraction efficiency or degree (E), were calculated. The best extraction efficiency, distribution coefficient, and loading factor were determined using 3-methyl-1-butanol diluent as values of 92.63, 12.25, and 0.195, respectively. The linear solvation energy relationship (LSER) model was regressed for the experimental results of the distribution coefficient with the regression coefficient (R-2) as 0.96. Besides, the equilibrium model for the extraction degree of alcohols has been applied and compared with experimental data.en_US
dc.description.sponsorshipIstanbul University [16710]en_US
dc.description.sponsorshipThis work was supported by the Research Fund of Istanbul University Project No. 16710.en_US
dc.identifier.doi10.1021/je5003362
dc.identifier.endpage2125en_US
dc.identifier.issn0021-9568
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-84902326800en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2120en_US
dc.identifier.urihttps://doi.org/10.1021/je5003362
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4329
dc.identifier.volume59en_US
dc.identifier.wosWOS:000337336700047en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAmer Chemical Socen_US
dc.relation.ispartofJournal Of Chemical And Engineering Dataen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleDistribution of Penicillin G from the Aqueous Phase to the Organic Phase Using Amberlite LA-2 Extractant in Different Diluentsen_US
dc.typeArticleen_US

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