Distribution of Penicillin G from the Aqueous Phase to the Organic Phase Using Amberlite LA-2 Extractant in Different Diluents
Küçük Resim Yok
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Amer Chemical Soc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Benzyl penicillin, known as penicillin G (PG), is a beta-lactam antibiotic and also a weak monocarboxylic acid. The penicillin G extraction from aqueous solution by Amberlite LA-2 in different diluents, that is, octan-1-ol, nonan-1-ol, 3-methyl-1-butanol, ethyl ethanoate, propyl ethanoate, 4-methylpentan-2-one, octan-2-one, octane, and decane has been studied. According to experimental results, some thermodynamic parameters, such as distribution coefficients (K-D), loading factors (Z), and the extraction efficiency or degree (E), were calculated. The best extraction efficiency, distribution coefficient, and loading factor were determined using 3-methyl-1-butanol diluent as values of 92.63, 12.25, and 0.195, respectively. The linear solvation energy relationship (LSER) model was regressed for the experimental results of the distribution coefficient with the regression coefficient (R-2) as 0.96. Besides, the equilibrium model for the extraction degree of alcohols has been applied and compared with experimental data.
Açıklama
Anahtar Kelimeler
Kaynak
Journal Of Chemical And Engineering Data
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
59
Sayı
6
