Determination of Antifungal Activity Against Invasive Candidiasis Agents and Trace Element Content of Fig Tree Latex Samples Obtained From Trabzon Province

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dc.authorid107955en_US
dc.authorid282775en_US
dc.authorid175428en_US
dc.authorid243533en_US
dc.contributor.authorÜnlü, Özge
dc.contributor.authorAlkan, Fatma Ateş
dc.contributor.authorÖzsobacı, Nural Pastacı
dc.contributor.authorÖzyüksel, Sedanur
dc.contributor.authorDemirci, Mehmet
dc.date.accessioned2021-12-25T07:39:24Z
dc.date.available2021-12-25T07:39:24Z
dc.date.issued2021
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractCandidiasis is a major health concern causing both morbidity and mortality. The increasing prevalence of antimicrobialresistant fungi associated with life-threatening systemic mycoses, led a constant need for new antifungal agents. Herbalmedicines have been tried for this purpose for centuries. The antifungal effect of fig tree latex has been reported and some traceelements such as zinc were associated with antifungal effects. The aim of this study was to determine the trace element contentand in-vitro antifungal activity of fig tree latex sample against Candida. albicans, C. glabrata, C. tropicalis and C. krusei. Figtree latex samples were obtained from four different fig tree at Trabzon province in July 2019. The broth microdilutiontechnique was performed to investigate antifungal activity against standard Candida strains and trace elements level weredetected with Inductively Coupled Plasma Optical Emission Spectrophotometer (ICP-OES) analyzer. The most powerfulantifungal activity was reached at a concentration of 0.5 for C. albicans and C. tropicalis, and at a concentration of 0.125 forC. krusei and C. glabrata in fig tree latex. According to trace element analysis, magnesium had the highest level, followed bycalcium and phosphorus. Selenium, aluminium, lead and nickel levels were too low to be measured. As a conclusion, fig treelatex has an antifungal potential against Candida species and this may be caused by the high level of magnesium that it contains,however more studies are needed to understand the therapeutic effects of fig tree latex.en_US
dc.identifier.citationInt. J. Adv. Eng. Pure Sci. 2021, 33(3):499-504en_US
dc.identifier.doi10.7240/jeps.933913
dc.identifier.issn1307-9085
dc.identifier.trdizinid457817en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/457817
dc.identifier.urihttps://doi.org/10.7240/jeps.933913
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherInternational Journal of Advances in Engineering and Pure Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.subjectFig tree latexen_US
dc.subjectFicus caricaen_US
dc.subjectCandidaen_US
dc.subjectAntifungal activityen_US
dc.subjectTrace elementsen_US
dc.titleDetermination of Antifungal Activity Against Invasive Candidiasis Agents and Trace Element Content of Fig Tree Latex Samples Obtained From Trabzon Provinceen_US
dc.title.alternativeTrabzon Bölgesinden İzole Edilen İncir Ağacı Latekslerinin İnvazif Kandidiyazis Etkenlerine Karşı Antifungal Aktivitesinin ve Eser Element Düzeylerinin İncelenmesien_US
dc.typeArticleen_US

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