Correction to: Synergistic Effect of Thymoquinone and Nystatin in the Treatment of Oral Candidiasis; an in Vitro Study

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dc.authorid243468en_US
dc.contributor.authorAltan Şallı, Gülay
dc.contributor.authorvd.
dc.date.accessioned2023-03-09T09:52:38Z
dc.date.available2023-03-09T09:52:38Z
dc.date.issued2022
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractThe efectiveness of antifungal agents may be insufcient against resistant strains in some cases of oral candidiasis. The aim of this study was to evaluate the antifungal efect of thymoquinone against Candida albicans, Candida tropicalis, Candida glabrata and Candida krusei strains and the synergistic antifungal activity of these strains in combination with nystatin. To evaluate in vitro antifungal activity and interactions between thymoquinone and nystatin, substances were tested against Candida albicans ATCC 10,231, C. tropicalis ATCC 750, C.krusei ATCC 6258 and C. glabrata ATCC 2001 standard strains both individually and combinationally via microdilution method. MIC and ?FIC index value were analysed. The Kruskal Wallis test and Bonferroni test were used for statistical evaluations. Statistical signifcance was set at p<0.05. A statistically signifcant diference was observed between the mean ranks of all Candida species and doses of thymoquinone, nystatin, and the combination thymoquinone-nystatin (p<0.05). MIC values for thymoquinone were determined as 15 ?g/mL for C. albicans, C. tropicalis and C. krusei while it was 30 ?g/mL for C. glabrata. Moreover, MIC for nystatin was found as 1.875 ?g/mL for C. albicans, C. tropicalis and C. krusei, whereas it was 7.5 ?g/mL in C. glabrata. Interaction assays and ?FIC index value revealed that, TQ and nystatin have a synergistic efect against to all strains. Thymoquinone was found to have antifungal activity on Candida species and synergistic efect when combined with nystatin.en_US
dc.identifier.doi10.1007/s10266-021-00673-6
dc.identifier.issn0370-2693
dc.identifier.pmid34714482en_US
dc.identifier.scopus2-s2.0-85118384388en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s10266-021-00673-6
dc.identifier.wosWOS:000712733100002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherThe Society of The Nippon Dental Universityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.subjectThymoquinoneen_US
dc.subjectCandidaen_US
dc.subjectAntifungal drugsen_US
dc.subjectSynergistic efecten_US
dc.subjectOral candidiasisen_US
dc.titleCorrection to: Synergistic Effect of Thymoquinone and Nystatin in the Treatment of Oral Candidiasis; an in Vitro Studyen_US
dc.typeArticleen_US

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