Local Use of Rifampicin for Surgical Site Infection after Lumbar Microdiscectomy

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dc.authorid313748en_US
dc.authorid150384en_US
dc.contributor.authorÇetin, Eyüp
dc.contributor.authorYücel, Murat
dc.date.accessioned2023-03-10T05:48:43Z
dc.date.available2023-03-10T05:48:43Z
dc.date.issued2022
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractObjective: To investigate the effect of local use of rifampicin (RIF) on the development of postoperative surgical site infection (SSI) after lumbar microdiscectomy. Study Design: Observational study. Place and Duration of Study: Van YuzuncuYil University Medical School Neurosurgery Clinic, between 2020 and 2022. Methodology: This retrospective study reviewed the clinical and laboratory records of 178 patients who underwent lumbar microsurgery. After lumbar microsurgery, one ampoule of rifampicin (RIF) (250 mg) was locally injected into the surgical site in 62 patients (RIF group), while the remaining 116 patients (non-RIF group) received no injection into the surgical site after lumbar microsurgery. Normal distribution of data was analysed using Kolmogorov-Smirnov test. Continuous variables were compared using Mann-Whitney U test and categorical variables were compared using chi-square test or Fisher’s exact test as needed. Results: In the postoperative period, local infection developed in one patient in the RIF group, while local infection developed in 11 and deep infection developed in three of the patients in the non-RIF group. Moreover, the risk of local infection development was significantly higher in the non-RIF group compared to the RIF group. The rate of superficial SSI was lower in the RIF group compared to the non-RIF group. No significant difference was observed between the two groups with regard to the rate of deep SSI. Conclusion: Postoperative infection is an extremely important clinical condition manifesting in the form of superficial or deep SSI. The utmost care and necessary precautions should be taken to avoid postoperative infections. Intraoperative antibiotic prophylaxis is the most effective method in preventing postoperative spinal infections.en_US
dc.identifier.doi10.29271/jcpsp.2022.10.1284
dc.identifier.issn1996-1944
dc.identifier.pmid36205272en_US
dc.identifier.scopus2-s2.0-85139316265en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2022.10.1284
dc.identifier.wosWOS:000886033700010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCOLL PHYSICIANS & SURGEONS PAKISTANen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.subjectInfectionen_US
dc.subjectLumbar microdiscectomyen_US
dc.subjectRifampicinen_US
dc.subjectLocal infectionen_US
dc.subjectDeep infectionen_US
dc.titleLocal Use of Rifampicin for Surgical Site Infection after Lumbar Microdiscectomyen_US
dc.typeArticleen_US

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