Evaluation of Hemoglobin and Hematocrit Values by the CO-Oximetry and Cyanide-Free Sodium Lauryl Sulphate Methods: A Retrospective Study

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dc.contributor.authorHocaoğlu, Fatma Sinem
dc.contributor.authorSerin, Huriye
dc.contributor.authorOğuz, Osman
dc.date.accessioned2023-03-09T12:17:12Z
dc.date.available2023-03-09T12:17:12Z
dc.date.issued2022
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractIntroduction: Blood gas analyzers (BGA) have recently been widely used as a rapid testing devices for the determination of hemoglobin (Hb) in the intensive care units and emergency services of hospitals. We compared the Hb and calculated hematocrit (Hct) values by the CO-oximetry and cyanide-free sodium lauryl sulphate (SLS) methods. Methods: Between January and June 2019, 12,049 patients who applied to the emergency department of İstanbul Training and research Hospital, for whole blood count and venous blood gas analysis were included. Samples were analyzed using SLS- Hb and CO-oximetry methods. Bland-Altman plot and Passing-Bablok regression analysis were performed to evaluate the accordance of the methods. Results: The correlation coefficients of the methods for Hb and Hct were 0.89 and 0.87, respectively (p<0.0001). Passing Bablok regression analysis showed a significant deviation from linearity (p<0.01). Bland-Altman plot showed insufficient agreement between of the two methods for each variable. Bias % calculated as 2.5% for Hb, and 1.1% for Hct. Total error calculated as 4.08% for Hb. Total error of CO-oximetric Hb value was within the limits of allowable total error. Conclusion: Although each test shows a significant deviation from linearity, BGA’s could be used for Hb measurements since the bias and total error were still acceptable.en_US
dc.identifier.doi10.4274/imj.galenos.2022.92845
dc.identifier.issn2452-3186
dc.identifier.scopusqualityQ2en_US
dc.identifier.trdizinid1123298en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1123298
dc.identifier.urihttps://doi.org/10.4274/imj.galenos.2022.92845
dc.identifier.wosWOS:000847358400008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGALENOS PUBL HOUSEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.subjectBlood gas analyzersen_US
dc.subjectCO-oxymetryen_US
dc.subjectHemoglobinen_US
dc.subjectSodium lauryl sulphateen_US
dc.subjectMethod comparisonen_US
dc.titleEvaluation of Hemoglobin and Hematocrit Values by the CO-Oximetry and Cyanide-Free Sodium Lauryl Sulphate Methods: A Retrospective Studyen_US
dc.typeArticleen_US

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