Biosensing Platforms for Cardiac Biomarker Detection

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dc.contributor.authorGerdan, Zeynep
dc.contributor.authorSaylan, Yeseren
dc.contributor.authorDenizli, Adil
dc.date.accessioned2024-03-13T10:35:12Z
dc.date.available2024-03-13T10:35:12Z
dc.date.issued2024
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractMyocardial infarction (MI) is a cardiovascular disease that occurs when there is an elevated demand for myocardial oxygen as a result of the rupture or erosion of atherosclerotic plaques. Globally, the mortality rates associated with MI are steadily on the rise. Traditional diagnostic biomarkers employed in clinical settings for MI diagnosis have various drawbacks, prompting researchers to investigate fast, precise, and highly sensitive biosensor platforms and technologies. Biosensors are analytical devices that combine biological elements with physicochemical transducers to detect and quantify specific compounds or analytes. These devices play a crucial role in various fields including healthcare, environmental monitoring, food safety, and biotechnology. Biosensors developed for the detection of cardiac biomarkers are typically electrochemical, mass, and optical biosensors. Nanomaterials have emerged as revolutionary components in the field of biosensing, offering unique properties that significantly enhance the sensitivity and specificity of the detection systems. This review provides a comprehensive overview of the advancements and applications of nanomaterial-based biosensing systems. Beginning with an exploration of the fundamental principles governing nanomaterials, we delve into their diverse properties, including but not limited to electrical, optical, magnetic, and thermal characteristics. The integration of these nanomaterials as transducers in biosensors has paved the way for unprecedented developments in analytical techniques. Moreover, the principles and types of biosensors and their applications in cardiovascular disease diagnosis are explained in detail. The current biosensors for cardiac biomarker detection are also discussed, with an elaboration of the pros and cons of existing platforms and concluding with future perspectives.en_US
dc.description.sponsorshipTrkiye Bilimsel ve Teknolojik Arastirma Kurumu [(BIDEB) 2247-D, 121C226]; Scientific and Technological Research Council of Turkey (TUBITAK) Directorate of Science Fellowshipsen_US
dc.description.sponsorshipDr. Yeseren Saylan thanks the Scientific and Technological Research Council of Turkey (TUBITAK) Directorate of Science Fellowships and Grant (BIDEB) 2247-D Programme (Project No: 121C226).en_US
dc.identifier.doi10.1021/acsomega.3c06571
dc.identifier.endpage9960en_US
dc.identifier.issn2470-1343
dc.identifier.issue9en_US
dc.identifier.scopus2-s2.0-85186071430en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage9946en_US
dc.identifier.urihttps://doi.org/10.1021/acsomega.3c06571
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4309
dc.identifier.volume9en_US
dc.identifier.wosWOS:001167956900001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAmer Chemical Socen_US
dc.relation.ispartofAcs Omegaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleBiosensing Platforms for Cardiac Biomarker Detectionen_US
dc.typeReview Articleen_US

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