Accuracy of the 24-h urine protein excretion value in patients with preeclampsia: correlation with instant and 24-h urine protein/creatinine and albumin/creatinine ratios

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dc.contributor.authorDogan, Suat
dc.contributor.authorSel, Gorker
dc.contributor.authorArikan, Inan Ilker
dc.contributor.authorHarma, Mehmet Ibrahim
dc.contributor.authorHarma, Muge
dc.contributor.authorBarut, Aykut
dc.contributor.authorOzmen, Ulku
dc.date.accessioned2024-03-13T10:35:20Z
dc.date.available2024-03-13T10:35:20Z
dc.date.issued2019
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractThe aim of this study was to determine the accuracy of the 24-h urine collection in preeclamptic pregnant women. This study included 65 singletons with preeclampsia and 53 singleton patients in a control-matched group. The ratio of inaccurate 24-h urine collection was measured by calculating expected urine creatinine excretion according to the proportion of pre-pregnancy weight and the lean body mass (LBM) of the patients. Comparisons were made between the accurately-collected 24-h urine protein excretion rates and the instant and 24-h urine protein/creatinine (P/Cr) and albumin/creatinine (A/Cr) ratios. Twenty-four-hour urine collection used to diagnose patients with preeclampsia was incorrectly collected 15-73.5% of the time among the patients and the control group. Instant and 24-h urine P/Cr and A/Cr ratios were correlated with total 24-h proteinuria among the patients in whom urine was collected correctly. Considering the 24-h urine P/Cr ratio, rather than the 24-h urine protein excretion value, is a better way to diagnose preeclampsia.IMPACT STATEMENT What is already known on this subject? Twenty-four-hour urine collection is considered as the gold standard of diagnosing proteinuria in preeclampsia, in case of the correctly collected. What do the results of this study add? Generally, in the literature the correctness of 24-h proteinuria is not questioned. However, it is actually quite important in daily practice to make the correct diagnosis of the proteinuria not to misdiagnose preeclampsia.en_US
dc.identifier.doi10.1080/01443615.2019.1586854
dc.identifier.endpage1080en_US
dc.identifier.issn0144-3615
dc.identifier.issn1364-6893
dc.identifier.issue8en_US
dc.identifier.pmid31177888en_US
dc.identifier.scopus2-s2.0-85068259616en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1075en_US
dc.identifier.urihttps://doi.org/10.1080/01443615.2019.1586854
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4374
dc.identifier.volume39en_US
dc.identifier.wosWOS:000487807900006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofJournal Of Obstetrics And Gynaecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject24-h urineen_US
dc.subjectinstant urineen_US
dc.subjectproteinuriaen_US
dc.subjectpreeclampsiaen_US
dc.subjectproteinen_US
dc.subjectcreatinineen_US
dc.titleAccuracy of the 24-h urine protein excretion value in patients with preeclampsia: correlation with instant and 24-h urine protein/creatinine and albumin/creatinine ratiosen_US
dc.typeArticleen_US

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