Evaluation of right side foetal myocardial performance index in pregestational and gestational diabetes mellitus

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dc.contributor.authorSenol, Gokalp
dc.contributor.authorAslan Cetin, Berna
dc.contributor.authorEsin, Didem
dc.contributor.authorTobas Selcuki, Nura Fitnat
dc.contributor.authorTayyar, Ahmet
dc.contributor.authorTurhan, Ugur
dc.contributor.authorButun, Zafer
dc.date.accessioned2024-03-13T10:35:21Z
dc.date.available2024-03-13T10:35:21Z
dc.date.issued2022
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractThe aim of our study is to investigate the myocardial performance index (MPI) of the right side of the foetal heart in pregestational and gestational diabetes mellitus and to compare it with non-diabetic pregnancies. This prospective cross-sectional study was conducted between August 2018 and March 2019 at Kanuni Sultan Suleyman Research and Training Hospital. Women with pregestational or gestational diabetes mellitus at 24-34 weeks of gestation were included in the study and non-diabetic pregnant women were included as the control group. MPI of the right side of the foetal heart were evaluated and compared between the groups. A total of 65 pregestational or gestational diabetic patients and 65 non-diabetic patients were included in the study. Isovolumetric contraction time and isovolumetric relaxation time values were significantly longer in the diabetic group (p < .001). Ejection time values were significantly shorter in the diabetic group (p < .001). MPI values were significantly higher in the diabetic group than the non-diabetic group (p < .001). In conclusion, MPI of the right side of the foetal heart is significantly higher in pregestational and gestational diabetes than in the non-diabetic group.IMPACT STATEMENT What is already known on this subject? Gestational diabetes mellitus causes foetal cardiomyopathy and foetal diastolic dysfunction. Myocardial performance index (MPI) is a non-invasive, Doppler-derived myocardial performance assessment that is independent of both heart rate and ventricular anatomy. What do the results of this study add? MPI of the right side of the foetal heart was significantly higher in pregestational and gestational diabetes than in the non-diabetic group. There was no difference in right ventricular MPI between pregestational and gestational groups in diabetic pregnancies, and between insulin using and not insulin using groups. What are the implications of these findings for clinical practice and/or further research? Our study results are promising. MPI of the right side of the foetal heart is significantly higher in pregestational and gestational diabetes than in the non-diabetic group. Prospective cohort studies evaluating serial MPI and evaluating by postpartum foetal echocardiography are needed to evaluate possible adverse effects of diabetes on foetal cardiac functions.en_US
dc.identifier.doi10.1080/01443615.2021.1882971
dc.identifier.endpage96en_US
dc.identifier.issn0144-3615
dc.identifier.issn1364-6893
dc.identifier.issue1en_US
dc.identifier.pmid33938355en_US
dc.identifier.scopus2-s2.0-85105191203en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage91en_US
dc.identifier.urihttps://doi.org/10.1080/01443615.2021.1882971
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4376
dc.identifier.volume42en_US
dc.identifier.wosWOS:000646425700001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofJournal Of Obstetrics And Gynaecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMyocardial performance indexen_US
dc.subjectgestational diabetes mellitusen_US
dc.subjectright hearten_US
dc.titleEvaluation of right side foetal myocardial performance index in pregestational and gestational diabetes mellitusen_US
dc.typeArticleen_US

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