Cardiac electrical and structural alterations in preeclampsia

dc.contributor.authorAksu, Ekrem
dc.contributor.authorCuglan, Bilal
dc.contributor.authorTok, Abdullah
dc.contributor.authorCelik, Enes
dc.contributor.authorDoganer, Adem
dc.contributor.authorSokmen, Abdullah
dc.contributor.authorSokmen, Gulizar
dc.date.accessioned2024-03-13T10:35:27Z
dc.date.available2024-03-13T10:35:27Z
dc.date.issued2022
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractBackground Preeclampsia increases the risk of cardiovascular mortality and morbidity both during pregnancy and long term after the labor by causing cardiac changes that may lead to atrial and ventricular arrhythmias. Objective We aimed to investigate noninvasive predictors of atrial and ventricular arrhythmias and cardiac structural changes in preeclampsia. Methods The study included 34 preeclampsia patients as the study group and 33 healthy pregnant women as the control group. The presence of fragmented QRS morphology, P dispersion, QT dispersion, Tp-e/QTc ratio, inter- and intra-atrial electromechanical delay, left ventricular mass index was evaluated in the groups by 12 lead- ECG and standard and tissue Doppler echocardiography. Results Left ventricular mass index and relative wall thickness, and E/Em ratio was significantly higher in preeclampsia. Inter- and intra-atrial electromechanical delay and Tp-e were prolonged, and P dispersion, QT dispersion, and Tp-e/QTc ratio were increased significantly in patients with preeclampsia. In addition, fragmented QRS morphology was seen in 76.5% of patients with preeclampsia while it was present in only 27.3% of the control group (p < .001). Conclusion Preeclampsia causes significant cardiac structural and electrocardiographic alterations that may increase the risk of atrial and/or ventricular arrhythmias. A more thorough and earlier cardiac assessment and closer follow-up of these patients would be useful to avoid further complications.en_US
dc.identifier.doi10.1080/14767058.2021.1895742
dc.identifier.endpage10en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue1en_US
dc.identifier.pmid33678092en_US
dc.identifier.scopus2-s2.0-85102173822en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.1080/14767058.2021.1895742
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4433
dc.identifier.volume35en_US
dc.identifier.wosWOS:000626477900001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArrhythmiaen_US
dc.subjectelectromechanical delayen_US
dc.subjectfQRSen_US
dc.subjectmyocardial performance indexen_US
dc.subjectpreeclampsiaen_US
dc.titleCardiac electrical and structural alterations in preeclampsiaen_US
dc.typeArticleen_US

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