Determination of cerebral blood flow velocity and microembolic signals in essential thrombocytosis by transcranial doppler ultrasonography

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dc.contributor.authorCinar, Ahmet
dc.contributor.authorCetin, Guven
dc.contributor.authorAltintas Kadirhan, Ozge
dc.contributor.authorTurgut, Seda
dc.contributor.authorEkinci, Iskender
dc.contributor.authorAsil, Talip
dc.date.accessioned2024-03-13T10:35:21Z
dc.date.available2024-03-13T10:35:21Z
dc.date.issued2021
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractObjectives The goal of treatment in essential thrombocytosis (ET) is to prevent vascular complications such as thrombosis and hemorrhage. This study aimed to evaluate the risk of cerebrovascular microembolism in ET patients due to detection of microembolic signals (MES) and measure cerebral blood flow velocity (CBFV) by Transcranial Doppler (TCD) ultrasonography. Material and Methods In this prospective case-control study, forty patients with diagnosed ET and age and sex-matched forty healthy controls were examined by the TCD sonography. Results The ET group had a higher rate of MES (8/40) in the right MCA than that in the control group (none), as measured by TCD. Five patients had MES at the left MCA compared to that in no subjects in the control group. The comparison of the ET and control groups in terms of CBFV parameters showed significantly lower end-diastolic FV at the right MCA in the ET group compared to that in the control group (p < 0.05). On the other hand; both pulsatility and resistance indices in the right and left MCA and the ratios of systolic to diastolic blood flow rates in the right and left MCA were significantly higher in the ET group than that in the control group. Discussion This study revealed that MES seems to be more common in patients with ET despite treatment. We could suggest that ET patients should be monitored more closely to address the potential risk of developing a cerebrovascular disease, which can be estimated by detection MES and raised CBFV, combine antiplatelet therapies to standard treatments.en_US
dc.description.sponsorshipBezmialem Vakif Universitesi [12.2013/26]en_US
dc.description.sponsorshipThis work was supported by the Bezmialem Vakif Universitesi [12.2013/26].en_US
dc.identifier.doi10.1080/01616412.2020.1833147
dc.identifier.endpage163en_US
dc.identifier.issn0161-6412
dc.identifier.issn1743-1328
dc.identifier.issue2en_US
dc.identifier.pmid33050838en_US
dc.identifier.scopus2-s2.0-85092609651en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage157en_US
dc.identifier.urihttps://doi.org/10.1080/01616412.2020.1833147
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4385
dc.identifier.volume43en_US
dc.identifier.wosWOS:000577383300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofNeurological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcerebral blood flow velocityen_US
dc.subjectcerebrovascular diseasesen_US
dc.subjectessential thrombocytosisen_US
dc.subjectmicroembolic signalsen_US
dc.subjecttranscranial doppler ultrasonographyen_US
dc.titleDetermination of cerebral blood flow velocity and microembolic signals in essential thrombocytosis by transcranial doppler ultrasonographyen_US
dc.typeArticleen_US

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