Improvement of Mechanical and Biological Properties of PLA/HNT Scaffolds Fabricated by Foam Injection Molding: Skin Layer Effect and Laser Texturing

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dc.contributor.authorEryildiz, M.
dc.contributor.authorAltan, M.
dc.contributor.authorOdabas, S.
dc.date.accessioned2024-03-13T10:33:06Z
dc.date.available2024-03-13T10:33:06Z
dc.date.issued2021
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractPolylactic acid (PLA) is one of the important materials for orthopedic regenerative engineering applications due to its biodegradability and biocompatibility. Nonetheless, PLA may show insufficient mechanical strength for some bone replace-ment applications. Halloysite nanotube (HNT) is one of the non-toxic, biocompatible reinforcement for improving me-chanical and biological properties of PLA for tissue engineer-ing applications. In this study, PLA/HNT scaffolds were pre-pared by chemical foam injection molding process. Laser surface texturing was applied on the skin layer of the injection molded scaffolds to enhance the cell viability and hydrophili-city of PLA. The effects of HNT concentration on cell mor-phology, mechanical and thermal properties, cell viability and biodegradation profile of the scaffolds were studied. The results demonstrated that cell viability increased by 43 % in PLA/HNT scaffolds compared to neat PLA. Hydrophilicity of the scaffolds that have thick skin layer was enhanced by the laser surface texturing in two different designs and conse-quently, cell viability increased about 16%. Surface rough-ness measurements and water contact angle measurements have verified this result.en_US
dc.description.sponsorshipResearch Fund of the Yildiz Technical University [FDK-2018-3362]en_US
dc.description.sponsorshipThis work was supported by Research Fund of the Yildiz Technical University [Project Number: FDK-2018-3362] .en_US
dc.identifier.doi10.1515/ipp-2020-4090
dc.identifier.endpage576en_US
dc.identifier.issn0930-777X
dc.identifier.issn2195-8602
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85120059556en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage564en_US
dc.identifier.urihttps://doi.org/10.1515/ipp-2020-4090
dc.identifier.urihttps://hdl.handle.net/20.500.12662/3753
dc.identifier.volume36en_US
dc.identifier.wosWOS:000722427700008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofInternational Polymer Processingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleImprovement of Mechanical and Biological Properties of PLA/HNT Scaffolds Fabricated by Foam Injection Molding: Skin Layer Effect and Laser Texturingen_US
dc.typeArticleen_US

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