Optical Coherence Tomography Findings in Cannabis Users

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dc.contributor.authorDayi, Ali
dc.contributor.authorDayi, Ozlem
dc.contributor.authorKurt, Emel
dc.contributor.authorYorguner, Nese
dc.date.accessioned2024-03-13T10:33:23Z
dc.date.available2024-03-13T10:33:23Z
dc.date.issued2020
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractObjective: In this study, we aimed to evaluate the effects of cannabis use on the retinal nerve fiber layer (RNFL) and the macular ganglion cell - inner plexiform layer GCL-IPL using optical coherence tomography (OCT). Method: This prospective, comparative study included 26 cannabis users who were evaluated at the Psychiatry Outpatient Unit of Mus State Hospital and 27 age and gender matched healthy controls. OCT was performed on both groups. The RNFL and GCL - IPL thicknesses, measured automatically by OCT, were recorded and compared between the groups. Results: The sociodemographic parameters of the two groups did not differ. The mean retinal nerve fiber thickness and thickness at the superior, nasal, inferior quadrants were not significantly different; but there was a significant difference at the temporal quadrant (p=0,022). In the analysis of macular ganglion cell - inner plexiform layer, the mean values as well as the infetotemporal, inferior, inferonasal and superonasal quadrants did not show significant differences. But there was a statistically significant decrease in the superior and superotemporal quadrants (p=0,006, p=0,027). Conclusion: These findings suggest that cannabis use leads to the thinning on retinal layers. As it is an easily observable part of the brain, evaluating retinal nerve fiber and ganglion cell layer with OCT may be important for monitoring toxic and degenerative effects in cannabis users.en_US
dc.identifier.doi10.5080/u25205
dc.identifier.endpage243en_US
dc.identifier.issn1300-2163
dc.identifier.issue4en_US
dc.identifier.pmid33454935en_US
dc.identifier.scopus2-s2.0-85100225330en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage239en_US
dc.identifier.urihttps://doi.org/10.5080/u25205
dc.identifier.urihttps://hdl.handle.net/20.500.12662/3928
dc.identifier.volume31en_US
dc.identifier.wosWOS:000616944700003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkiye Sinir Ve Ruh Sagligi Dernegien_US
dc.relation.ispartofTurk Psikiyatri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOptical coherenceen_US
dc.subjectcannabisen_US
dc.subjectretinal nerve fiberen_US
dc.titleOptical Coherence Tomography Findings in Cannabis Usersen_US
dc.typeArticleen_US

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