Synthetic Exploitation of Halogenated Alkenes Containing EWG: Polysubstituted Sulfanyl Dinitro Butadienes from Sequential Nucleophilic Substitutions

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dc.contributor.authorIbis, Cemil
dc.contributor.authorTuyun, Amac Fatih
dc.date.accessioned2024-03-13T10:33:38Z
dc.date.available2024-03-13T10:33:38Z
dc.date.issued2011
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractOur novel approach starts from a 1,1,3,4-tetrachloro-2,4-dinitrobuta-1,3-diene (5) being one of the most prominent members of this relatively new class of synthetic building blocks. Because of its multifunctional chemical behavior, polyhalogenated nitrobuta-1,3-dienes proved to be versatile reagents in the synthesis of a large variety of sulfurated, (hetero) cyclic, and acyclic derivatives. We describe our studies concerning successive nucleophilic vinylic substitution reactions of dinitrobuta-1,3-diene in order to establish the reactivity profile of this precursor and determine whether this precursor could be used for the synthesis of many dinitrodiene analogues offering new methodology for the synthesis of polyfunctional precursors that are difficult to access. Some of the resulting perfunctionalized 2,4-dinitrobuta-1,3-dienes are subjected to further transformations to give promising candidates with respect to biological activity.en_US
dc.description.sponsorshipIstanbul University [6414]en_US
dc.description.sponsorshipWe gratefully thank the Research Fund of the Istanbul University for financial support of this work (Project No: 6414).en_US
dc.identifier.endpage871en_US
dc.identifier.issn1570-1794
dc.identifier.issn1875-6271
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-81155123952en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage861en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4059
dc.identifier.volume8en_US
dc.identifier.wosWOS:000299613600007en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherBentham Science Publ Ltden_US
dc.relation.ispartofCurrent Organic Synthesisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectClick chemistryen_US
dc.subjectDienesen_US
dc.subjectNitro compoundsen_US
dc.subjectNitroalkenesen_US
dc.subjectPersulfurated Alkenesen_US
dc.subjectPolyhalogenated Compoundsen_US
dc.subjectPolysulfanyl Buta-1,3-dienesen_US
dc.subjectSulfidesen_US
dc.titleSynthetic Exploitation of Halogenated Alkenes Containing EWG: Polysubstituted Sulfanyl Dinitro Butadienes from Sequential Nucleophilic Substitutionsen_US
dc.typeArticleen_US

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