Nucleophilic substitution reactions of 1,4-naphthoquinone and biologic properties of novel S-, S,S-, N-, and N,S-substituted 1,4-naphthoquinone derivatives

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dc.contributor.authorIbis, Cemil
dc.contributor.authorTuyun, Amac Fatih
dc.contributor.authorBahar, Hakan
dc.contributor.authorAyla, Sibel Sahinler
dc.contributor.authorStasevych, Maryna V.
dc.contributor.authorMusyanovych, Rostyslav Ya.
dc.contributor.authorKomarovska-Porokhnyavets, Olena
dc.date.accessioned2024-03-13T10:30:41Z
dc.date.available2024-03-13T10:30:41Z
dc.date.issued2014
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractA novel series of S-, S,S-, N- and N,S-substituted 1,4-naphthoquinone derivatives were synthesized and evaluated for their antibacterial and antifungal activity. Among the synthesized compounds especially 10a and 11b have been discovered as an antibacterial or antifungal agents, and 15f is the most effective compound against M. luteum as potent antifungal. The structures of the novel products were characterized by micro analysis, UV/Vis, H-1 NMR, C-13 NMR, and MS. The electrochemical properties of some of the novel 1,4-naphthoquinone derivatives were also investigated by cyclic voltammetry.en_US
dc.description.sponsorshipTUBITAK [109T617]; State Agency on Science, Innovations and Informatization of Ukraine [M/309-2011]en_US
dc.description.sponsorshipThe financial support from TUBITAK for Ukraine-Turkey agreement gratefully acknowledged (Project No. 109T617) and from State Agency on Science, Innovations and Informatization of Ukraine (Project No. M/309-2011).en_US
dc.identifier.doi10.1007/s00044-013-0806-y
dc.identifier.endpage2149en_US
dc.identifier.issn1054-2523
dc.identifier.issn1554-8120
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84898952740en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2140en_US
dc.identifier.urihttps://doi.org/10.1007/s00044-013-0806-y
dc.identifier.urihttps://hdl.handle.net/20.500.12662/3496
dc.identifier.volume23en_US
dc.identifier.wosWOS:000331003400049en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Birkhauseren_US
dc.relation.ispartofMedicinal Chemistry Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject1,4-Naphthoquinoneen_US
dc.subjectAminesen_US
dc.subjectThiolsen_US
dc.subjectAntibacterial activityen_US
dc.subjectAntifungal activityen_US
dc.titleNucleophilic substitution reactions of 1,4-naphthoquinone and biologic properties of novel S-, S,S-, N-, and N,S-substituted 1,4-naphthoquinone derivativesen_US
dc.typeArticleen_US

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