Cranial magnetic resonance imaging findings in 167 patients with spina bifida aperta: a retrospective study

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dc.contributor.authorSezen, Gulseli Berivan
dc.contributor.authorAlatas, Ibrahim
dc.contributor.authorSaygi, Haci Mehmet
dc.contributor.authorAndrada Ay, Larisa
dc.contributor.authorCelik, Cenk
dc.contributor.authorBoyali, Osman
dc.date.accessioned2026-01-31T15:08:10Z
dc.date.available2026-01-31T15:08:10Z
dc.date.issued2025
dc.departmentİstanbul Beykent Üniversitesi
dc.description.abstractObjectiveThis study aimed to comprehensively evaluate the spectrum and prevalence of cranial magnetic resonance imaging (MRI) findings in a substantial cohort of patients diagnosed with spina bifida aperta. Furthermore, the study sought to contextualize these findings by comparing them with existing literature, thereby contributing to a better understanding of the neurological landscape associated with this common neural tube defect.Materials and methodsA retrospective analysis was conducted on the cranial MRI scans of 167 patients who received a diagnosis of spina bifida aperta between January 2022 and December 2024 at Gaziosmanpa & scedil;a Research and Training Hospital and & Idot;stanbul Demiroglu Bilim University Florance Nightingale Hospital Spina Bifida and Fetal Centre. Demographic data and a detailed assessment of various cranial anomalies, including cerebellar ectopia (Chiari type II malformation), posterior fossa depth, hydrocephalus, tectal beaking, and other less frequent findings, were meticulously recorded and analyzed.ResultsOur analysis revealed a high frequency of cranial anomalies in this patient population. The most prevalent findings were decreased posterior fossa depth (81.4%), cerebellar ectopia consistent with Chiari type II malformation (79.6%), hydrocephalus (69.9%), and tectal beaking (63.5%). Additionally, a range of other cranial abnormalities, including cervicomedullary kink, corpus callosum dysgenesis, and various cortical malformations, were observed with varying frequencies.ConclusionThe significant prevalence of cranial anomalies, particularly those affecting the posterior fossa and ventricular system, underscores the intricate relationship between spinal and intracranial development in spina bifida aperta. Early identification of these anomalies through cranial MRI is crucial for anticipating potential neurological complications, guiding timely interventions, and ultimately optimizing the neurodevelopmental outcomes and long-term care strategies for these patients. This study provides valuable epidemiological data that aligns with and contributes to the existing body of knowledge in the field.
dc.identifier.doi10.1007/s00381-025-07054-2
dc.identifier.issn0256-7040
dc.identifier.issn1433-0350
dc.identifier.issue1
dc.identifier.pmid41275036
dc.identifier.scopus2-s2.0-105022619640
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org./10.1007/s00381-025-07054-2
dc.identifier.urihttps://hdl.handle.net/20.500.12662/10611
dc.identifier.volume41
dc.identifier.wosWOS:001620155000003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofChilds Nervous System
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260128
dc.subjectSpina bifida aperta
dc.subjectCranial MRI
dc.subjectPosterior fossa
dc.subjectCerebellar ectopia
dc.subjectChiari type 2
dc.subjectHydrocephalus
dc.subjectTectal beaking
dc.titleCranial magnetic resonance imaging findings in 167 patients with spina bifida aperta: a retrospective study
dc.typeReview Article

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