Association between parity and lumbar spine degenerative disorders in young women

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dc.contributor.authorCevik, Serdar
dc.contributor.authorYilmaz, Hakan
dc.contributor.authorKaplan, Atilla
dc.contributor.authorYetkinel, Selcuk
dc.contributor.authorEvran, Sevket
dc.contributor.authorCalis, Fatih
dc.contributor.authorAkkaya, Enes
dc.date.accessioned2024-03-13T10:35:22Z
dc.date.available2024-03-13T10:35:22Z
dc.date.issued2020
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractIntroduction: Estrogen helps to maintain the health of collagen-containing tissues including the intervertebral disc. Estrogen deficiency after menopause negatively affects the quality of vertebral end plates and induces development of degenerative disc disease (DDD). However, there is no study examining the relationship between parity and spinal degeneration in young women. The aim of this study was to define the relationship between parity and development of vertebral endplate signal changes and DDD in young premenopausal women. Materials and methods: This case-control case study included 224 patients aged 20-40 years with a history of low back pain for at least 3 months. Pfirrmann's grade, Modic changes (MCs), and Schmorl's nodes (SNs) were graded based on magnetic resonance images. Patients' parity, demographics, body mass index, physical activity level, and disability scores were assessed using a questionnaire. Results: The prevalence of abnormal total Pfirrmann's score (>10) and MCs was higher in primiparous patients than multiparous and grand-multiparous; however, it was not statistically significant. The presence of SN was statistically significantly associated with low parity. According to multivariate logistic regression analysis, it was found that the number of births increases by 1 unit, the abnormality in Pfirrmann's score decreases by 1.36 times. Conclusions: This cross-sectional study shows that parity is associated with DDD and vertebral end plate changes. SNs were significantly associated with parity. Modic changes and DDD were less common in grand multipara and multipara young women than in primipara women. These results indicate that low parity may possibly be associated with the development of spinal degeneration.en_US
dc.identifier.doi10.1080/02688697.2019.1701628
dc.identifier.endpage175en_US
dc.identifier.issn0268-8697
dc.identifier.issn1360-046X
dc.identifier.issue2en_US
dc.identifier.pmid31851846en_US
dc.identifier.scopus2-s2.0-85076732649en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage172en_US
dc.identifier.urihttps://doi.org/10.1080/02688697.2019.1701628
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4392
dc.identifier.volume34en_US
dc.identifier.wosWOS:000503549300001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBritish Journal Of Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectParityen_US
dc.subjectModic changesen_US
dc.subjectSchmorl's nodesen_US
dc.subjectestrogenen_US
dc.subjectdegenerative disc diseaseen_US
dc.titleAssociation between parity and lumbar spine degenerative disorders in young womenen_US
dc.typeArticleen_US

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