Design, FEA and experimental validation of 3D-printed PLA/PCL intervertebral cages for lumbar spinal fusion

dc.authorid0000-0002-6943-9586
dc.authorid0000-0001-9670-2426
dc.authorid0000-0002-2683-560X
dc.contributor.authorEryildiz, Meltem
dc.contributor.authorKadirhan, Ozge Altintas
dc.contributor.authorDemirci, Mehmet
dc.contributor.authorKarakus, Aleyna
dc.contributor.authorAltan, Mihrigul Eksi
dc.date.accessioned2026-01-31T15:08:52Z
dc.date.available2026-01-31T15:08:52Z
dc.date.issued2025
dc.departmentİstanbul Beykent Üniversitesi
dc.description.abstractThis study examines the mechanical performance of novel PLA/PCL intervertebral cage designs for lumbar spinal fusion, using FEA and experimental compression testing. Four 3D-printed cage designs with varying graft window sizes and structural volumes were tested for load-bearing capacity. Experimental compressive strengths ranged from 43.36 MPa for Cage 4-50.43 MPa for Cage 3, all meeting the mechanical requirements of spinal applications. Cage 2, with a dual-window design, exhibited optimal load distribution and the highest compressive strength (50.00 MPa), indicating enhanced stability. Conversely, Cage 4, prioritizing graft space with the largest window, demonstrated the lowest compressive strength, revealing a trade-off between graft window size and structural support. FEA findings aligned well with experimental results, showing consistent trends in load distribution. Cage 2 exhibited the lowest von Mises stress, while Cage 4 had the highest stress concentrations, indicating vulnerability to deformation. This consistency between FEA and experimental data validates the reliability of FEA in evaluating cage designs. The findings suggest that PLA/PCL cages are viable alternatives to conventional materials, advancing the development of sustainable, patient-specific spinal fusion solutions. This study emphasizes the critical role of design in achieving a balance between structural support and potential for effective graft support in spinal implants.
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [123M748]; TUBITAK
dc.description.sponsorshipThis study was supported by Scientific and Technological Research Council of Turkey (TUBITAK) under the Grant Number 123M748. The authors thank to TUBITAK for their supports.
dc.identifier.doi10.1515/mt-2024-0484
dc.identifier.endpage1028
dc.identifier.issn0025-5300
dc.identifier.issn2195-8572
dc.identifier.issue6
dc.identifier.scopus2-s2.0-105004064334
dc.identifier.scopusqualityQ2
dc.identifier.startpage1014
dc.identifier.urihttps://doi.org./10.1515/mt-2024-0484
dc.identifier.urihttps://hdl.handle.net/20.500.12662/10777
dc.identifier.volume67
dc.identifier.wosWOS:001477562900001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWalter De Gruyter Gmbh
dc.relation.ispartofMaterials Testing
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260128
dc.subject3D printing
dc.subjectPLA/PCL
dc.subjectintervertebral cage design
dc.subjectfinite element analysis (FEA)
dc.subjectcompressive strength
dc.titleDesign, FEA and experimental validation of 3D-printed PLA/PCL intervertebral cages for lumbar spinal fusion
dc.typeArticle

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