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Öğe Diz Osteoartritli Hastalarda Eklem İçi Viskosuplement Enjeksiyonunun İzokinetik Kas Gücü Üzerine Etkileri(2021) Duymaz, Tomris; Ünal, Mehmet; Hakan, Mehmet Tolgahan; Ural, İbrahim HalilGİRİŞ ve AMAÇ: Diz osteoartriti hayat kalitesini önemli derecede etkileyen yaygın bir hastalıktır. Rehabilitasyon protokolleri diz eklemi üzerindeki yükü azaltmak amacıyla kas güçlendirme egzersizleri içermelidir. bu çalışmada intraartiküler olarak uygulanan hyaluronik asit, kondroitin sülfat ve glukozamin içeren viskosuplementasyon enjeksiyonlarının diz kaslarının izokinetik kuvvetleri üzerindeki etkilerini araştırdık. YÖNTEM ve GEREÇLER: Çift-kör ve randomize yapılan bu çalışmada demografik veriler ve izokinetik kas gücü ölçümü Biodex (System 3) ile yapıldı. Enjeksiyondan önce ve 3 ay sonra kuadriseps kasının 60°/sn ve 240°/sn açısal hızlarında izokinetik kas gücü testi uygulandı. SPSS for Windows programı ile istatistiksel analizler yapıldı. BULGULAR: 60°/sn ve 240°/sn açısal hızlarında yapılan izokinetik testlerde istatistiksel olarak anlamlı fark bulundu. Diz osteoartriti tedavisinde hyaluronik asit, kondroitin sülfat ve glukozamin içeren viskosuplementasyon enjeksiyonlarının kuadriseps ve hamstring kaslarında total ve fonksiyonel izokinetik kas gücünü arttırdığı saptandı. TARTIŞMA ve SONUÇ: Hyaluronik asit, kondroitin sülfat ve glukozamin içeren viskosuplementasyon enjeksiyonları kuadriseps ve hamstring kaslarında 60°/sn ve 240°/sn açısal hızlarında izokinetik kas gücünün artmasını sağlamaktadır. Tedavi protokollerinde daha fazla yer alabileceği düşünülebilir.Öğe The Effect of Chest Physiotherapy After Bariatric Surgery on Pulmonary Functions, Functional Capacity, and Quality of Life(Springer, 2020) Duymaz, Tomris; Karabay, Onder; Ural, Ibrahim HalilPurpose The aim of this study was to investigate the effect of chest physiotherapy (CP) applied to patients undergoing bariatric surgery on pulmonary functions, dyspnea levels, functional capacity, and quality of life. Methods The patients were randomized and divided into two groups each comprising 74 patients. CP and mobilization was applied to the patients in the first group, and only mobilization was applied to the patients in the second group. The treatment of the patients was started on the first postoperative day and continued until the postoperative 4th day. CP and mobilization were applied twice a day, 8 times in total. The following parameters were evaluated: arterial blood gas, oxygen saturation, respiratory function test for pulmonary functions, pulmonary artery pressure for pulmonary hypertension, Borg dyspnea score for severity of dyspnea, 6-min walk test(6MWT) for functional capacity, Nottingham Health Profile for quality of life. Results The mean age of the patients was 38.00 +/- 7.04 years. Compared with pretreatment and posttreatment dyspnea score, 6MWT, oxygen saturation, vital capacity, tidal volume, PEF, pulmonary arterial pressure, and quality of life were significantly higher in patients who underwent CP compared with the control group(p = 0.008, 0.004, 0.005, 0.027, 0.029, 0.028, 0.007, 0.012).There was a significant improvement in all the parameters of the patients who underwent chest physiotherapy when compared with the intragroup comparisons, whereas in the control group, only 6MWT and quality of life score showed a significant improvement in the border (p = 0.037, 0.046). Conclusion Postoperative CP applied to patients who had bariatric surgery showed that the patients improved their respiratory functions, regulated arterial blood gases, increased oxygen saturation, functional capacity and quality of life, and decreased dyspnea levels.Öğe Impact of body weight-based dosing of palonosetron and ondansetron on postoperative nausea and vomiting following laparoscopic sleeve gastrectomy: a randomized, double-blind study(Taylor & Francis Ltd, 2024) Burcu, Buesra; Hacim, Nadir Adnan; Caliskan, Ozan; Demirgan, Serdar; Aktokmakyan, Talar Vartanoglu; Meric, Serhat; Duymaz, TomrisBackground Postoperative nausea and vomiting (PONV) is a frequent adverse effect following laparoscopic sleeve gastrectomy. Palonosetron with a standard dosing (75 mu g) schedule has been questioned due to its low efficiency in obese patients. This study aimed to investigate the effectiveness and safety of the body weight-based dosing of palonosetron in managing PONV following laparoscopic sleeve gastrectomy. Methods A single-center, prospective, double-blinded randomized study was conducted between August 2021 and December 2021. Patients who underwent laparoscopic sleeve gastrectomy were prospectively recruited in the study. One hundred patients were randomly divided into palonosetron (Group P) and ondansetron (Group O). The demographic and clinical variables were recorded. The primary outcome of the study was the incidence of PONV between the two groups during the hospitalization. The secondary outcomes were the number of rescue anti-emetic and analgesic medications and the Functional Living Index-Emesis scores. Results There were 50 patients in each group (Group P and Group O). There were significant differences in the scores of POVN, nausea, and vomiting favoring Group P. In Group P, the rate of patients using rescue anti-emetics was significantly lower. The incidence of complete response and proportion of patients with higher Functional Living Index-Emesis scores were significantly higher in patients using palonosetron. Conclusions The use of palonosetron significantly reduced the incidence of PONV following laparoscopic sleeve gastrectomy. There was a significant improvement in the scores of Functional Living Index-Emesis in patients using palonosetron.