Ultrasound-guided Dextrose Prolotherapy for Refractory Piriformis Syndrome: A Retrospective Study

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dc.contributor.authorZure, Mert
dc.contributor.authorOZYIGIT, Elif
dc.contributor.authoroğuzhanasiltürk, dilek ün
dc.contributor.authorSahbaz, Tugba
dc.date.accessioned2026-01-31T15:02:17Z
dc.date.available2026-01-31T15:02:17Z
dc.date.issued2025
dc.departmentİstanbul Beykent Üniversitesi
dc.description.abstractObjective: Piriformis syndrome is a neuromuscular condition characterized by sciatic nerve compression by the piriformis muscle, resulting in buttock pain radiating to the posterior thigh. While physical therapy and corticosteroid injections are commonly used, treatment-refractory cases remain challenging. Dextrose prolotherapy is a regenerative technique gaining interest, but its efficacy in piriformis syndrome is not well established. Materials and Methods: This retrospective study included 43 patients diagnosed with piriformis syndrome based on clinical criteria, including a positive FAIR test and at least one additional provocative maneuver. Patients received three sessions of ultrasound-guided injections of 5% dextrose (1 mL per site, 5 mL total) targeting the piriformis musculotendinous junction at 3-week intervals. Pain and functional status were assessed at baseline, 1-month, and 3-month follow-ups using the visual analog scale (VAS) and oswestry disability index (ODI). Patient satisfaction and adverse events were also recorded. Results: Mean VAS scores decreased from 7.6 to 2.3 (p<0.001), and median ODI scores improved from 48 to 20 over three months (p<0.001). Eighty-eight per- cent of patients reported satisfaction with the treatment. No major complications were observed; minor adverse events were mild and self-limiting. Conclusion: Ultrasound-guided dextrose prolotherapy significantly reduced pain and improved function in patients with refractory piriformis syndrome. These findings support its role as a minimally invasive treatment option, warranting further prospective studies.
dc.identifier.doi10.14744/cm.2025.44366
dc.identifier.endpage337
dc.identifier.issn2822-6771
dc.identifier.issue4
dc.identifier.startpage332
dc.identifier.trdizinid1357371
dc.identifier.urihttps://doi.org/10.14744/cm.2025.44366
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1357371
dc.identifier.urihttps://hdl.handle.net/20.500.12662/10368
dc.identifier.volume17
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofComprehensive medicine
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR-Dizin_20260128
dc.subjectProlotherapy
dc.subjectDextrose
dc.subjectpiriformis syndrome
dc.subjectultrasound-guided injections
dc.subjectsciatic pain
dc.titleUltrasound-guided Dextrose Prolotherapy for Refractory Piriformis Syndrome: A Retrospective Study
dc.typeArticle

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