Prognostic Significance of Glutathione Peroxidase(GSH-Px) Levels in Lumbar Degenerative DiscDisease

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dc.contributor.authorAkdeniz, Fatma Tuba
dc.contributor.authorYaltırık, Cumhur
dc.contributor.authorİsbir, Turgay
dc.contributor.authorSümerkent, Kadir
dc.contributor.authorYılmaz, Seda Güleç
dc.contributor.authorÖzdoğan, Selçuk
dc.date.accessioned2024-03-13T09:50:09Z
dc.date.available2024-03-13T09:50:09Z
dc.date.issued2020
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractObjective: In this study, the main aim was to research whether decreased antioxidant activity was manifesting the intervertebral disc degeneration in a population in which the degeneration could be compatible with their ages.Material and Method: The study group consisted of 39 patients with lumbar disc degeneration (LDD) and 37 healthy controls. Patient data including age, symptoms, neurological examination findings, lumbar MRI findings, Oswestry Disability Index (ODI) scores, and Visual Analogue Scale of pain (VAS) were used. Human Glutathione peroxidase (GSH-Px) level was determined using the Enzyme-Linked Immunosorbent Assay (ELISA) method.Results: Serum GSH-Px levels were significantly lower in the patients with LDD when compared to the healthy controls (p=0.011).Conclusions: In the present study, we demonstrated that, in addition to environmental factors, there is a correlation between GSHPx enzyme deficiency and lumbar disc degeneratioen_US
dc.identifier.endpage71en_US
dc.identifier.issn2630-6050
dc.identifier.issue2en_US
dc.identifier.startpage67en_US
dc.identifier.trdizinid406849en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/406849
dc.identifier.urihttps://hdl.handle.net/20.500.12662/2476
dc.identifier.volume10en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofEXPERIMEDen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titlePrognostic Significance of Glutathione Peroxidase(GSH-Px) Levels in Lumbar Degenerative DiscDiseaseen_US
dc.typeArticleen_US

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