Expressions of cytochrome p450 family and molecular mechanisms in breast cancer

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dc.contributor.authorOguztüzün S.
dc.contributor.authorTürk B.A.
dc.contributor.authorYildirim I.
dc.date.accessioned2024-03-13T10:01:23Z
dc.date.available2024-03-13T10:01:23Z
dc.date.issued2020
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractCytochrome P450 enzymes (CYPs) is an important group of the phase I enzymes family. They protect the metabolism of environmental chemicals, and their genetic variations which are associated with the risk of several forms of cancer including breast cancer. The expressions of individual CYPs were observed in different types of human breast cancers. The changes of these expressions of CYPs may enhance the development and proliferation of breast tumor cells and provoke tumor development through activation of procarcinogens or expression of CYP genes that take place in the biosynthesis of steroids, especially estrogen. Moreover, it affects the etiology of breast cancer and they may also change the response to treatment. That's why the expression of CYP has a critical role in breast cancer. Therefore, this study was carried out to compare the molecular mechanism of CYP family members on breast cancer and the distinct biological processes with each other. © 2020 by Nova Science Publishers, Inc. All rights reserved.en_US
dc.identifier.endpage201en_US
dc.identifier.isbn9781536182842
dc.identifier.isbn9781536181555
dc.identifier.scopus2-s2.0-85144534327en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage191en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12662/3170
dc.identifier.volume75en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNova Science Publishers, Inc.en_US
dc.relation.ispartofHorizons in Cancer Researchen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectActivityen_US
dc.subjectApoptosisen_US
dc.subjectBreast canceren_US
dc.subjectCytochrome (P450)en_US
dc.subjectEstrogenicen_US
dc.subjectMolecular mechanismen_US
dc.subjectROSen_US
dc.titleExpressions of cytochrome p450 family and molecular mechanisms in breast canceren_US
dc.typeBook Chapteren_US

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