Factors Associated with Neurodevelopmental Retardation in Preterm Infants: A Single-center Experience

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dc.contributor.authorÇolak, Rüya
dc.contributor.authorKıvılcım, Meltem
dc.contributor.authorÖzdemir, Senem Alkan
dc.contributor.authorErgon, Ezgi Yangın
dc.contributor.authorÇalkavur, Şebnem
dc.contributor.authorYıldırım, Tülin Gökmen
dc.date.accessioned2024-03-13T09:50:02Z
dc.date.available2024-03-13T09:50:02Z
dc.date.issued2022
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractObjective: Today, the survival rate of low-birth-weight infants has increased thanks to supportive care. However, various permanent health problems, especially neurodevelopmental retardation, can be seen in these infants. This study investigates the risk factors associated with neurodevelopmental retardation, especially hypocarbia, in this patient group. Methods: All patients who were hospitalized in our neonatal ıntensive care unit between January 1 and December 31, 2016, with a gestational age of less than 32 weeks, without congenital anomalies, and who came for regular follow-up were included in this study. Demographic, clinical and laboratory data were obtained retrospectively from file records. The neurodevelopment of the patients was evaluated between 18 and 24 months with the Bayley Scales of Infants and Toddler Development, Second Edition (Bayley-II).The demographic, clinical and laboratory parameters of the patients with and without neurodevelopmental retardation were compared. Results: Neurodevelopmental retardation was observed in 9 (16.1%) of the 56 patients included in the study. No neurodevelopmental retardation was detected due to cerebral palsy, hearing impairment or visual impairment. When the patient groups with and without neurodevelopmental retardation were compared in terms of demographic, clinical and laboratory parameters, birth weight and first and fifthminute Apgar scores were lower in patients with neurodevelopmental retardation, while mechanical ventilation requirement, reintubation, convulsion, patent ductus arteriosus treatment, hypotension, bronchopulmonary dysplasia, asphyxia, hyperglycemia and hypocarbia rate were higher (p<0.05). Conclusion: While providing mechanical ventilation support, in addition to the negative effects of hypercarbia on neurodevelopment, the negative effects of hypocarbia on neurodevelopment should also be kept in mind.en_US
dc.identifier.doi10.4274/forbes.galenos.2022.54227
dc.identifier.endpage302en_US
dc.identifier.issn2717-9443
dc.identifier.issn2757-5241
dc.identifier.issue3en_US
dc.identifier.startpage297en_US
dc.identifier.trdizinid1174510en_US
dc.identifier.urihttps://doi.org/10.4274/forbes.galenos.2022.54227
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1174510
dc.identifier.urihttps://hdl.handle.net/20.500.12662/2419
dc.identifier.volume3en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofForbes tıp dergisi (Online)en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleFactors Associated with Neurodevelopmental Retardation in Preterm Infants: A Single-center Experienceen_US
dc.typeArticleen_US

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