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    90-day Readmission Rates After Cholecystectomy: A Retrospective Cohort Study
    (Permanyer, 2022) Karabay, Önder; vd.
    Objective: Although readmission after surgical procedures has been recognized as a new problem, its association with cholecystectomy has not been solved. We aimed to investigate the rate of unplanned readmission after cholecystectomy and to evaluate the reasons and outcomes in these patients. Methods: All consecutive patients who underwent open and laparoscopic cholecystectomy were retrospectively evaluated. Hospital readmission within the post-operative first 90 days after the procedure was searched. The rate and reasons for hospital readmission were the primary outcomes. Results: There were 601 patients with a mean age of 53.2 ± 12.4 years. The rate of readmission was 6.16%. Obesity (p = 0.001), number of coexisting disease (p = 0.039), conversion to open surgery (p = 0.002), development of intraoperative complications (p < 0.001), use of drain (p = 0.001), and length of hospital stay > 1 day (p = 0.024) were significantly associated with higher readmission rates. Biliary surgical causes were detected in five patients (12.8%). Non-biliary surgical causes were seen in 34 patients (87.2%). Among these, post-operative pain, nausea, and vomiting were the most common diagnoses in 25 (67.6%) and 5 patients (12.8%). Conclusion: The readmission rate after cholecystectomy is low. Significant predictive factors may help physicians to be alerted during the discharge of the patients. Post-operative pain, nausea, and vomiting were the most common diagnoses.
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    Adaptive Metaheuristic-Based Methods for Autonomous Robot Path Planning: Sustainable Agricultural Applications
    (MDPI, 2022) Seyyedabbasi, Amir; vd.
    The increasing need for food in recent years means that environmental protection and sustainable agriculture are necessary. For this, smart agricultural systems and autonomous robots have become widespread. One of the most significant and persistent problems related to robots is 3D path planning, which is an NP-hard problem, for mobile robots. In this paper, efficient methods are proposed by two metaheuristic algorithms (Incremental Gray Wolf Optimization (I-GWO) and Expanded Gray Wolf Optimization (Ex-GWO)). The proposed methods try to find collision-free optimal paths between two points for robots without human intervention in an acceptable time with the lowest process costs and efficient use of resources in large-scale and crowded farmlands. Thanks to the methods proposed in this study, various tasks such as tracking crops can be performed efficiently by autonomous robots. The simulations are carried out using three methods, and the obtained results are compared with each other and analyzed. The relevant results show that in the proposed methods, the mobile robots avoid the obstacles successfully and obtain the optimal path cost from source to destination. According to the simulation results, the proposed method based on the Ex-GWO algorithm has a better success rate of 55.56% in optimal path cost.
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    Calorimetry with Extremely Fine Spatial Segmentation
    (Institute of Physics, 2022) Bilki, Burak; vd.
    Particle Flow Algorithms (PFAs) attempt to measure each particle in a hadronic jet individually, using the detector subsystem that provides the best energy/momentum resolution. Calorimeters that can exploit the power of PFAs emphasize spatial granularity over single particle energy resolution. In this context, the CALICE Collaboration developed the Digital Hadron Calorimeter (DHCAL). The DHCAL uses Resistive Plate Chambers (RPCs) as active media and is read out with 1 ´ 1 cm2 pads and digital (1-bit) resolution. In order to obtain a unique dataset of electromagnetic and hadronic interactions with unprecedented spatial resolution, the DHCAL went through a broad test beam program. In addition to conventional calorimetry, the DHCAL offers detailed measurements of event shapes, rigorous tests of simulation models and various analytical tools to improve calorimetric performance. Here we report on the results from the analysis of DHCAL data and comparisons with the Monte Carlo simulations
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    The Challenge of Unprecedented Floods and Droughts in Risk Management
    (NATURE PORTFOLIO, 2022) Çavuş, Yonca; vd.
    Risk management has reduced vulnerability to foods and droughts globally1,2, yet their impacts are still increasing3. An improved understanding of the causes of changing impacts is therefore needed, but has been hampered by a lack of empirical data4,5. On the basis of a global dataset of 45?pairs of events that occurred within the same area, we show that risk management generally reduces the impacts of foods and droughts but faces difculties in reducing the impacts of unprecedented events of a magnitude not previously experienced. If the second event was much more hazardous than the frst, its impact was almost always higher. This is because management was not designed to deal with such extreme events: for example, they exceeded the design levels of levees and reservoirs. In two success stories, the impact of the second, more hazardous, event was lower, as a result of improved risk management governance and high investment in integrated management. The observed difculty of managing unprecedented events is alarming, given that more extreme hydrological events are projected owing to climate change3. .
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    Comparison of the Efficiency of Magnetic-Activated Cell Sorting (MACS) and Physiological Intracytoplasmic Sperm Injection (PICSI) for Sperm Selection in Cases with Unexplained Infertility
    (JRI, 2022) Fındıklı, Necati; vd.
    Background: The cases with unexplained infertility may have an abnormality in their sperm chromatin structure. Sperm selection methods can be used to separate sperm with low DNA fragmentation. The purpose of this study was to compare the efficacy of physiological intracytoplasmic sperm injection (PICSI) with magnetic activated cell sorting (MACS) in assisted reproductive techniques in cases with un explained infertility. Methods: The semen samples were collected from couples with unexplained infer tility. After semen analysis and sperm DNA fragmentation (SDF) evaluations, sam ples were prepared with swim-up method. The rates of SDF in different fractions in cluding raw semen (n=20), swim-up (n=20), only motile sperm after swim-up (swim-up selection) (n=20), MACS sperm selection (n=20), only motile sperm after MACS (MACS selection) (n=20), and PICSI sperm selection (n=16) were evaluated. Also, the main sperm characteristics and fine morphology of sperm suspension after MACS were assessed. Statistical analysis was performed using GraphPad Prism. The p<0.05 was considered statistically significant. Results: DNA fragmentation index (DFI) values in PICSI and MACS groups were significantly reduced as compared to the swim-up group. The rate of this reduction was more pronounced in MACS (58.20±13.02) than PICSI (36.57±15.52) group. Al so, our results showed that MACS resulted in decreased sperm motility, with no al teration in their fine morphology. Conclusion: MACS was found to be more efficient in reduction of SDF rates than PICSI. However, none of the sperm selection techniques can not totally eliminated the spermatozoa with DNA fragmentation in the final sperm sample.
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    Correction to: Synergistic Effect of Thymoquinone and Nystatin in the Treatment of Oral Candidiasis; an in Vitro Study
    (The Society of The Nippon Dental University, 2022) Altan Şallı, Gülay; vd.
    The efectiveness of antifungal agents may be insufcient against resistant strains in some cases of oral candidiasis. The aim of this study was to evaluate the antifungal efect of thymoquinone against Candida albicans, Candida tropicalis, Candida glabrata and Candida krusei strains and the synergistic antifungal activity of these strains in combination with nystatin. To evaluate in vitro antifungal activity and interactions between thymoquinone and nystatin, substances were tested against Candida albicans ATCC 10,231, C. tropicalis ATCC 750, C.krusei ATCC 6258 and C. glabrata ATCC 2001 standard strains both individually and combinationally via microdilution method. MIC and ?FIC index value were analysed. The Kruskal Wallis test and Bonferroni test were used for statistical evaluations. Statistical signifcance was set at p<0.05. A statistically signifcant diference was observed between the mean ranks of all Candida species and doses of thymoquinone, nystatin, and the combination thymoquinone-nystatin (p<0.05). MIC values for thymoquinone were determined as 15 ?g/mL for C. albicans, C. tropicalis and C. krusei while it was 30 ?g/mL for C. glabrata. Moreover, MIC for nystatin was found as 1.875 ?g/mL for C. albicans, C. tropicalis and C. krusei, whereas it was 7.5 ?g/mL in C. glabrata. Interaction assays and ?FIC index value revealed that, TQ and nystatin have a synergistic efect against to all strains. Thymoquinone was found to have antifungal activity on Candida species and synergistic efect when combined with nystatin.
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    Demographic and clinical characteristics of inpatient stroke patients in Turkey
    (Turkish Society of Physical Medicine and Rehabilitation, 2022) Uçar, Demet; vd.
    Objectives: This study aims to assess the stroke rehabilitation facilities provided by university hospitals (UHs) and training and research hospitals (TRHs) and to evaluate the geographical disparities in stroke rehabilitation.Patients and methods: Between April 2013 and April 2014 a total of 1,529 stroke patients (817 males, 712 females; mean age: 61.7±14.0 years; range, 12 to 91 years) who were admitted to the physical medicine and rehabilitation clinics in 20 tertiary care centers were retrospectively analyzed. Demographic, regional and clinical characteristics, details of rehabilitation period, functional status, and complications were collected. Results: The median duration of stroke was five (range, 1 to 360) months. The ratio of the patients treated in the TRH in the Marmara region was 77%, but only 25% of the patients were living in the Marmara region. Duration of hospitalization was longer in the TRHs with a median of 28 days compared to those of UHs (median: 22 days) (p<0.0001). More than half of the patients (55%) were rehabilitated in the Marmara region. Time after stroke was the highest in the Southeast region with a median of 12 (range, 1 to 230) months and the lowest in the Aegean region with a median of four (range, 1 to 84) months. Conclusion: This study provides an insight into the situation of stroke rehabilitation settings and characteristics of stroke patients in Turkey. A standard method of patient evaluation and a registry system may provide data about the efficacy of stroke rehabilitation and may help to focus on the problems that hinder a better outcome
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    Design, construction and operation of the ProtoDUNE-SP Liquid Argon TPC
    (IOP Publishing Ltd, 2022) Bilki, Burak; vd.
    The ProtoDUNE-SP detector is a single-phase liquid argon time projection chamber (LArTPC) that was constructed and operated in the CERN North Area at the end of the H4 beamline. This detector is a prototype for the first far detector module of the Deep Underground Neutrino Experiment (DUNE), which will be constructed at the Sandford Underground Research Facility (SURF) in Lead, South Dakota, U.S.A. The ProtoDUNE-SP detector incorporates full-size components as designed for DUNE and has an active volume of 7 × 6 × 7.2 m3 . The H4 beam delivers incident particles with well-measured momenta and high-purity particle identification. ProtoDUNE-SP’s successful operation between 2018 and 2020 demonstrates the effectiveness of the single-phase far detector design. This paper describes the design, construction, assembly and operation of the detector components.
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    Detection of Deregulated miRNAs in Childhood Epileptic Encephalopathies
    (SPRINGERNATURE, 2022) Hayretdağ, Ceyda; Ünalp, Aycan; vd.
    The term “epileptic encephalopathy” is used to describe a possible relationship between epilepsy and developmental delay. The pathogenesis of developmental encephalopathies, independent of epilepsy, can be defned by genetic control mechanisms. The aim of this study was to investigate the use of miRNAs as serum biomarkers for the determination and discrimination of epileptic encephalopathies. Whole blood samples obtained from 54 individuals in 2 groups designated as epilepticencepha lopathy patients’ group (n=24) and healthy controls (n=30) were included in this study. The expression levels of10 miRNAs were determined using qRT-PCR. After the determination of expression levels, the correlation of upregulated miRNA levels and Ki67 index was calculated using Pearson correlation test. The comparison of epileptic encephalopathy patients’ group with healthy controls revealed the upregulation of one miRNAs (hsa-miR-324-5p) and downregulation of three miRNAs (hsa-miR-146a-5p, hsa-miR-138-5p, hsa-miR-187-3p). It has been determined that miRNAs with altered expression are an important factor in the formation of epileptic seizures and seizure-induced neuronal death. The fact that processes that play a key role in epiloptogenesis are under the control of miRNAs causes miRNAs to become meta-controllers of gene expres sion in the brain.We thought that further studies are needed to prove that especially hsa-miR-146a-5p, hsa-miR-138-5p, and hsa-miR-187-3p can be used as epileptic encephalopathy biomarkers. The detection of disease-specifc miRNAs could contribute to the development of precision treatments
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    Development of an Argon Light Source as a Calibration and Quality Control Device for Liquid Argon Light Detectors
    (MDPI, 2022) Tosun, Mehmet; Bilki, Burak; vd.
    The majority of future large-scale neutrino and dark matter experiments are based on liquid argon detectors. Since liquid argon is also a very effective scintillator, these experiments also have light detection systems. The liquid argon scintillation wavelength of 127 nm is most commonly shifted to the visible range by special wavelength shifters or read out by the 127 nm sensitive photodetectors that are under development. The effective calibration and quality control of these active media is still a persisting problem. In order to respond to this need, we developed an argon light source which is based on plasma generation and light transfer across a MgF2 window. The light source was designed as a small, portable and easy-to-operate device to enable the acquisition of performance characteristics of several square meters of light detectors. Here, we report on the development of the light source and its performance characteristics.
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    Development of an Argon Light Source as a Calibration and Quality Control Device for Liquid Argon Light Detectors
    (Institute of Physics, 2022) Tosun, Mehmet; Bilki, Burak; vd.
    The majority of future large-scale neutrino and dark matter experiments are based on liquid argon detectors. Since liquid argon is also a very effective scintillator, these experiments also have light detection systems. 127 nm wavelength of the liquid argon scintillation leads to the development of specialized light detectors, mostly based on wavelength shifters, and recently photodetectors sensitive to deeper UV. The effective calibration and quality control of these newly developed detectors is still a persisting problem. In order to respond to this need, we developed an argon light source which is based on plasma generation and light transfer across a MgF2 window. The light source is designed as a small, portable and easy to operate device to enable the acquisition of performance characteristics of several square meters of light detectors at once. Here we report on the development of the light source and its preliminary performance characteristics.
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    Development of Novel Designs of Resistive Plate Chambers
    (Institute of Physics, 2022) Bilki, Burak; vd.
    A novel design of Resistive Plate Chambers (RPCs), using only a single resistive plate, was developed and tested. Based on this design, prototype chambers of size ranging from 10 cm ´ 10 cm to 32 cm ´ 48 cm were constructed and tested with cosmic rays and particle beams. The tests confirmed the viability of this new approach for calorimetric applications where the particle rates do not exceed 1 kHz/cm2, such as CALICE digital calorimeters. The chambers also have improved single-particle response, such as a pad multiplicity close to unity.In addition to this development, we probed a new technique to mitigate limitations associated with common RPC gases compatible with the environment. The technique is based on electron multiplication in a thin layer of high secondary electron yield material coating on the anode plane. Here we report on the construction of various different glass RPC designs, and their performance measurements in laboratory tests and with particle beams.
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    Development of Novel Designs of Resistive Plate Chambers
    (MDPI, 2022) Bilki, Burak; vd.
    Resistive Plate Chambers (RPCs) are a key active media of the muon systems of current and future collider experiments as well as the CALICE (semi-)digital hadron calorimeter. The outstanding issues with RPCs can be listed as the loss of efficiency for the detection of particles when subjected to high particle fluxes and the limitations associated with the common RPC gases. We developed novel RPC designs with: low resistivity glass plates; a single resistive plate; and a single resistive plate and a special anode plate coated with high secondary electron emission yield material. The cosmic and beam tests confirmed the viability of these new approaches for calorimetric applications. The chambers also have improved single-particle response, such as a pad multiplicity close to unity. Here, we report on the construction of various different glass RPC designs and their performance measurements in laboratory tests and with particle beams. We also discuss future test plans, which include the long-term performance tests of the newly developed RPCs, investigation of minimal gas flow chambers, and feasibility study for the large-size chambers.
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    Effectiveness of Anodal otDCS Following with Anodal tDCS Rather than tDCS Alone for Increasing of Relative Power of Intrinsic Matched EEG Bands in Rat Brains
    (MDPI, 2022) Kaptan, Zulal; vd.
    Background: This study sought to determine whether (1) evidence is available of inter actions between anodal tDCS and oscillated tDCS stimulation patterns to increase the power of endogenous brain oscillations and (2) the frequency matching the applied anodal otDCS’s frequency and the brain’s dominant intrinsic frequency influence power shifting during stimulation pattern sessions by both anodal DCS and anodal oscillated DCS. Method: Rats received different anodal tDCS and otDCS stimulation patterns using 8.5 Hz and 13 Hz state-related dominant intrinsic frequencies of anodal otDCS. The rats were divided into groups with specific stimulation patterns: group A: tDCS–otDCS (8.5 Hz)–otDCS (13 Hz); group B: otDCS (8.5 Hz)–tDCS–otDCS (13 Hz); group C: otDCS (13 Hz)–tDCS–otDCS (8.5 Hz). Acute relative power changes (i.e., following 10 min stimulation ses sions) in six frequency bands—delta (1.5–4 Hz), theta (4–7 Hz), alpha-1 (7–10 Hz), alpha-2 (10–12 Hz), beta-1 (12–15 Hz) and beta-2 (15–20 Hz)—were compared using three factors and repeated ANOVA measurement. Results: For each stimulation, tDCS increased theta power band and, above bands alpha and beta, a drop in delta power was observed. Anodal otDCS had a mild increasing power effect in both matched intrinsic and delta bands. In group pattern stimulations, increased power of endogenous frequencies matched exogenous otDCS frequencies—8.5 Hz or 13 Hz—with more potent effects in upper bands. The power was markedly more potent with the otDCS–tDCS stimulation pattern than the tDCS–otDCS pattern. Significance: The findings suggest that the otDCS–tDCS pattern stimulation increased the power in matched intrinsic oscillations and, significantly, in the above bands in an ascending order. We provide evidence for the successful corporation between otDCS (as frequency-matched guidance) and tDCS (as a power generator) rather than tDCS alone when stimulating a desired brain intrinsic band (herein, tES specificity)
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    An Empirical Assessment of the Contagion Determinants in the Euro Area in a Period of Sovereign Debt Risk
    (Springer Science and Business Media Deutschland GmbH, 2022) Altınbaş, Hazar; vd.
    This paper uses learning methods and optimization techniques to investigate the determinants of shock propagation in the Euro area for the period 2001–2015. First, principal component analyses are used with country bond yields to identify sub periods and country groups; second, infuencing factors for country bond yields are investigated with random forest models; lastly, shock propagation among groups are examined with impulse response functions. Models in steps two and three are improved by using simulated annealing algorithm. The empirical fndings achieved can be particularly relevant for both investors and policymakers. Shedding light on the determinants of fnancial contagion may be in fact useful for investors who can derive relevant information about countries which are less sensitive to be afected by shocks, orienting thus their investment strategies. At the same time, policymakers could draw worthwhile and preventive hedging strategies and design the most suit able crisis management policies.
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    Evaluation of cognitive functions in adult individuals with COVID-19
    (Springer-Verlag Italia s.r.l., 2022) Ulu, Oğulcan; Akıncı, Büşra; Erkan Oğul, Özden; vd.
    Background and Purpose Cognitive defcits that are associated with coronavirus disease 2019 (COVID-19) and occur in the acute period are gaining importance. While most studies have focused on the elderly severely afected during acute infection, it remains unclear whether mild to moderate COVID-19 results in cognitive defcits in young patients. This study aims to evaluate the post-infection cognitive functions of young adults with mild to moderate symptoms of COVID-19. Methods A total of 100 adults with similar age and educational background were included in the study. Half of those had been infected with COVID-19 in the last 60 days (N=50), and the other half had not (N=50). Global cognitive skills of the participants were evaluated through Montreal Cognitive Assessment Scale (MoCA) and Clock-Drawing Test; memory functions with Öktem Verbal Memory Processes Test (Ö-VMPT); attention span with Digit Span Test; executive functions with Fluency Tests, Stroop Test, and Trail Making Test; visual perceptual skills with Rey Osterrieth Complex Figure Test (ROCF); and neuropsychiatric status with Neuropsychiatric Inventory (NPI). Evaluations were performed in the experimental group for 21 to 60 days from the onset of the disease, and throughout the study, in the control group. Results It was found that global cognitive skills, verbal memory, visual memory, executive function, and neuropsychiatric status were afected during COVID-19 (p<0.05). Conclusion When the cases were analyzed according to disease severity, no relationship was found between cognitive defcits and disease severity
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    Evaluation of the Coronal Malposition of the Volar Locking Plate in the Treatment of Distal Radius Fractures
    (CUREUS INC, 2022) Öç, Yunus; vd.
    Background and objectives: Literature does not show any studies regarding plate placement problems in the coronal plane of patients with volar plating due to distal radius fracture diagnosis. We aimed to investigate the functional and laboratory results of the coronal malposition of the volar locking plate in patients with distal radius fracture treated with internal fixation. Methods: In this retrospective study, we included patients who had volar plate fixation, were aged between 18 and 80, had no pathological fracture, had a minimum of six months of follow-up, and had the same rehabilitation protocol. We consider the angle subtended on the coronal axis between the distal radius long axis and the distal radius locking plate as coronal malposition. We named the coronal malposition angle the "AYE Angle." Patients with an AYE angle of over 1 degree were evaluated under group 1. Patients with an AYE angle of 0-1 degrees were evaluated under group 2. Radiological parameters were taken from AP-Lateral X-ray views. Superficial University System of Georgia (USG) examinations were applied to detect tendon problems. The DASH and QUICK-DASH scoring systems were used for clinical evaluation. Grip strength was measured with a dynamometer in all patients. All results were compared between the two groups. Results: Thirteen patients were female and 27 patients were male. Nineteen patients who had coronal malposition were added to group 1, while 21 patients who had no coronal malposition were added to group 2. Fifteen patients had normal USG results in group 2, while 18 patients had edema around the flexor pollicis longus (FPL) tendon as a result of USG in group 1. Statistically, a significant difference was detected between the two groups in terms of the amount of tenosynovitis around FPL (p=0.01). A statistically significant relationship was found between USG grading and malposition grading. The study revealed that a higher rate of USG grade 2 was found in patients with malposition grade 2 (90.9%), while a higher rate of USG grade 1 (50%) was observed in patients with malposition grade 1 (p=0.01). A statistically significant difference was not found between Soong grading and USG in terms of the level of tenosynovitis around the FPL tendon. The amount of tenosynovitis detected around the FPL tendon was 62.5% for Soong and grade 0 level, 60.7% for grade 1 level, and 50% for grade 2 level. There was no statistically significant difference between the two groups in the DASH and QUICK-DASH scoring systems (p=0.96). There was no statistically significant difference between the two groups in the grip strength(p=0.52). Conclusion: Coronal plate position in the treatment of the distal radius fracture is important to avoid potential flexor tendon problems. The volar plate position should be adjusted properly both in the coronal and sagittal axes.
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    Evaluation of the predictors of oral health-related quality of life among 3-5-year-old children with dental trauma
    (The International Committee of Medical Journal Editor’s (ICMJE) , 2022) Yılmaz, Dilek Özge; vd.
    This study evaluated the influence of socio-demographic, clinical, and parental psychological factors on oral health-related quality of life (OHRQoL) and determined their predictors in preschool-aged children with traumatic dental injury (TDI). The study sample consisted of 324 dyads of children and their parents attending the Clinics of Pediatric Dentistry at Istanbul University. After clinical examination, the Sense of Coherence (SOC), Generalized Self-Efficacy Scale, Early Childhood Oral Health Impact Scale, and Multidimensional Health Locus of Control Scale-MHLC questionnaires were administered to the parents. The statistical analyses included Spearman correlation coefficients, Mann–Whitney U tests, Kruskal–Wallis tests, multiple linear regression, and confirmatory factor analysis. Having mixed TDI a non-nuclear family, fewer children, and weak parental SOC were important predictors of worse overall OHRQoL and its sections of child and family. Lower internal health locus of control and dental pain due to TDI were predictors of worse overall OHRQoL and child impact, respectively. Consideration of these predictors may help oral health professionals to develop prevention and treatment programs for TDI and oral health literacy programs for families.
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    Evaluation of Upper Extremity Movement, Pain Intensity, and Respiratory Functions in Patients Who Received Thoracotomy Sparing the Serratus Anterior Muscle
    (European Journal of Therapeutics, 2022) Karaaslan, Yasemin; vd.
    Objective: To evaluate upper extremity movement, pain intensity, and respiratory functions in preoperative and postoperative periods in patients undergoing thoracotomy sparing the serratus anterior muscle (TSSAM). Methods: Forty-three patients (25 male and 18 female) were included in this prospective observational cohort type study. In the preoperative period and on postoperative days 1, 2, 3, and 5, ipsilateral shoulder range of motion was evaluated by a goniometer, pain intensity was evaluated by a visual analog scale (VAS), and respiratory functions were evaluated by spirometry. Results: When compared with preoperative values, shoulder flexion and abduction angle, forced expiratory volume in 1 second (FEV1), and functional vital capacity (FVC) decreased on postoperative day 1, while VAS significantly increased (P < .05). Shoulder flexion and abduction angle, FEV1, and FVC significantly increased and VAS significantly decreased on postoperative days 2, 3, and 5 compared to postoperative day 1 (P < .05). However, they could not reach preoperative values on postoperative day 5 (P < .05). On postoperative day 1, while there was a correlation between pain and flexion (r = ?0.438; P = .003) and abduction (r = ?0.503; P = .001) angles, no correlation was found between pain and FEV1 (r = ?0.189; P = .225) and FVC (r = 0.009; P = .953). There was no correlation between pain and flexion, abduction, FEV1, and FVC on postoperative days 2,3, and 5 (P > .05). Conclusions: Patients undergoing the TSSAM had less upper extremity range of motion and respiratory functions and more pain intensity in the early postoperative period than in the preoperative period. It was observed that pain and flexion and abduction angles were negatively correlated on postoperative day 1. In the postoperative period, they should be taken into account in the design/development of rehabilitation programs.
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    Evidence for X(3872) in Pb-Pb Collisions and Studies of its Prompt Production at root s(NN)=5.02 TeV
    (AMER PHYSICAL SOC, 2022) Gürpınar Güler, Emine; vd.
    The first evidence for X(3872) production in relativistic heavy ion collisions is reported. The X(3872) production is studied in lead-lead (Pb-Pb) collisions at a center-of-mass energy of s(NN)=5.02 TeV per nucleon pair, using the decay chain X(3872) ? J/??+?? ? ?+???+??. The data were recorded with the CMS detector in 2018 and correspond to an integrated luminosity of 1.7 nb?1. The measurement is performed in the rapidity and transverse momentum ranges jyj < 1.6 and 15 < pT < 50 GeV=c. The significance of the inclusive X(3872) signal is 4.2 standard deviations. The prompt X(3872) to ?2S yield ratio is found to be ?Pb-Pb = 1.08 0.49(stat) 0.52(syst), to be compared with typical values of 0.1 for pp collisions. This result provides a unique experimental input to theoretical models of the X(3872) production mechanism, and of the nature of this exotic state.