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    In Vitro Dielectric Properties of Rat Skin Tissue for Microwave Skin Cancer Detection
    (IEEE, 2019) Aydinalp, Cemanur; Joof, Sulayman; Yilmaz, Tuba; Ozsobaci, Nural Pastaci; Alkan, Fatma Ates; Akduman, Ibrahim
    Dermal tissue characterization based on dielectric properties can be utilized as a non-invasive method for diagnosis of skin cancers. To enable such technology, there is a need to develop techniques that can rapidly and accurately collect the dielectric properties of the skin tissues. Therefore, the current measurement techniques and tools has to be optimized for skin cancer detection. To this end, this study presents dielectric property measurements with open-ended coaxial probes having small apertures customized for detection of skin cancer. Relative permittivity and conductivity of rat skin tissue is characterized with open-ended coaxial probes with outer diameters of 0.9mm and 0.5mm between 0.5GHz-6GHz and the measurement results are compared with the traditional probes having diameter of 2.2mm. The results agree well with the reported literature data.
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    In-vivo Microwave Dielectric Properties of Healthy and Carcinogenic Rat Nasal Tissues from 500 MHz to 6 GHz
    (IEEE, 2019) Yilmaz, Tuba; Ozsobaci, Nural Pastaci; Alkan, Falma Ales; Kepil, Nuray; Akduman, Ibrahim
    Dielectric properties of rat nasal tissue and nasal carcinoma is given in this work between 500 MHz to 6 GHz. Nasal carcinoma is induced by oral administration of single dose 20 7,12-Dimethylbenz[a]anthracene (DMBA) dissolved in 1 ml olive oil to 47 days old Sprague Dawley (SD) rats. A granular tissue anomaly in one rat along with bleeding is observed after 15 weeks from the administration of the carcinogenic agent. In-vivo dielectric properties are collected both from the granular nasal carcinoma tissue and healthy counterpart with open-ended coaxial probe technique. A median dielectric property discrepancy is observed in the whole frequency range between the nasal carcinoma and healthy tissues.
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    Use of Hair as Matrix for Trace Elements Biomonitoring in Cattle and Roe Deer Sharing Pastures in Northern Italy
    (MDPI, 2024) Draghi, Susanna; Fehri, Nour Elhouda; Ates, Fatma; Ozsobaci, Nural Pastaci; Tarhan, Duygu; Bilgic, Bengu; Dokuzeylul, Banu
    Simple Summary This study investigates using hair analysis to monitor potentially toxic elements (PTEs) in cattle and roe deer sharing pastures in Northern Italy. PTEs include essential and non-essential elements that, if unbalanced in organisms, can lead to health issues. Hair analysis is a non-invasive method that allows retrospective evaluation of PTE exposure. Aluminum, As, Cd, Cr, Ni, Pb, Cu, Mg, Fe, and Zn were measured. Findings indicate significantly higher As levels in roe deer due to selective feeding, while Cd and Pb levels align with other studies. Cattle have lower Cu, Fe, and Zn levels, likely due to dietary differences. Elevated Cr and Ni in cattle suggest contamination or physiological differences. Hair analysis proves valuable for monitoring environmental PTE exposure, emphasizing interspecies differences and the potential of both animals as bioindicators.Abstract Intensive cattle breeding's environmental challenges are prompting shifts to extensive, pasture-based systems, influencing nutrient and pollutant uptake. PTEs are essential and non-essential elements, regularly found in the environment and organisms, and in which unbalances lead to health issues. Hair analysis, a non-invasive method, provides retrospective PTE exposure evaluation. This study aims to understand exposure and species-specific accumulation patterns of PTEs in cattle and roe deer sharing pastures in Northern Italy using the hair analysis. Aluminum, As, Cd, Cr, Ni, Pb, Cu, Mg, Fe, and Zn were quantified through the use of ICP-OES. Findings show As levels significantly higher in roe deer due to their selective feeding, while Cd and Pb levels align with other studies. Essential elements like Cu, Fe, and Zn are lower in cattle, possibly due to diet differences. Higher Cr and Ni levels in cattle suggest contamination or physiological differences in accumulation patterns. In conclusion, hair analysis is valuable for monitoring environmental PTE exposure, highlighting significant interspecies differences and the potential of both animals as bioindicators in shared grazing areas.