Yazar "Gulyasar, Tevfik" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    Evaluation of Some Element and Mineral Levels in Prescription and Non-Prescription Dog Diets
    (Univ Ljubljana, 2024) Or, Mehmet Erman; Bilgic, Bengu; Tarhan, Duygu; Ates, Fatma; Dokuzeylul, Banu; Gulyasar, Tevfik
    Various prescription diets prescribed by veterinarians for specific diseases in dogs have been developed and introduced to the market. Trace element and mineral levels, which are essential for healthy living conditions in animals, can differ in both prescription and non-prescription foods. In our study, it was aimed to determine the levels of some elements and minerals in various prescription and non-prescription dry foods used in dog nutrition and to evaluate their therapeutic importance. In the study, a total of 100 different prescription dry food formulated for hepatic diseases (H, n=25), renal diseases (R, n=25), gastrointestinal diseases (GI, n=25) and, allergic diseases (HA, n=25) were used. Non-prescription dry foods from different flavors and brands in the market were considered as the control group (C, n=50). Copper (Cu), Iron (Fe), Manganese (Mn), Zinc (Zn), Selenium (Se), Calcium (Ca), and Phosphorus (P) levels of all dry foods were analyzed by Inductively Coupled Plasma -Optical Emission Spectrometer (ICP-OES, Thermo iCAP 6000 series) and the results were compared between groups. Statistical analysis was evaluated using SPSS 21. Cu levels in GI and HA groups were higher than in the control group (p<0.05 and p<0.01, respectively). Fe levels were higher in the GI group and lower in the HA group than in the control group (p<0.05). Mn level was significantly higher in the H group compared to the control group (p<0.001). The Mn levels in GI and HA groups were higher than the control group (p<0.01). There was no statistical difference in Se and Zn levels between prescription and non-prescription dry foods. Ca and P levels in all groups were statistically lower than in the control group (p<0.001). There are significant differences in element and mineral levels in prescription and nonprescription dry foods. These values may be out of the legal limits determined by EU Regulation. Considering the therapeutic purpose of these prescription formulas, some element and mineral amounts were determined as inappropriate.
  • Küçük Resim Yok
    Öğe
    EVALUATION OF ZINC AND COPPER TOXICITY CAUSED BY INGESTION OF TURKISH COINS: AN IN VITRO STUDY
    (Polish Society Magnesium Research, 2020) Alkan, Fatma Ates; Kilinc, Evren; Gulyasar, Tevfik; Or, Mehmet Erman
    Coins are foreign objects that are commonly ingested by children and pets due to their shiny appearance and bright colors. The current study investigated whether Turkish coins can lead to zinc (Zn) and copper (Cu) toxicity as a result of exposure to simulated gastric juice (i.e. hydrochloric acid solution simulating the gastric environment). Five groups of coins were exposed to simulated gastric juice (0.15 N, pH:1-2) for a period of 4 (Group 1), 12 (Group 2), 24 (Group 3), 48 (Group 4), 72 (Group 5) and 120 h (Group 5) at body temp. (37 degrees C). Zinc and copper levels were determined in the gastric acid solution by using an inductively coupled plasma optical emission spectrophotometer (ICP-OES). The coins were also evaluated for corrosive damage and weight loss. Group 5 had statistically higher Cu and Zn levels versus the other groups. However, at body temp. (37 degrees C), copper and zinc levels increased steadily in parallel to the duration for which the coin remained in the stomach after ingestion. After 120-hour exposure at 37 degrees C, all coins had various types of damage compared to the baseline, such as color alteration, erosion, and visible surface cavities. The mechanisms relating to local and systemic copper and zinc toxicity caused by coin ingestion is yet to be clarified for both Turkish and international coins. Therefore, it can be foreseen that intervention is required in the first 24 h after ingesting 5 kurus coins and, unless removed spontaneously in 48 h, such intervention is needed for the other coins.