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    Evaluation of Some Element and Mineral Levels in Prescription and Non-Prescription Dog Diets
    (Univ Ljubljana, 2024) Or, Mehmet Erman; Bilgic, Bengu; Tarhan, Duygu; Ates, Fatma; Dokuzeylul, Banu; Gulyasar, Tevfik
    Various prescription diets prescribed by veterinarians for specific diseases in dogs have been developed and introduced to the market. Trace element and mineral levels, which are essential for healthy living conditions in animals, can differ in both prescription and non-prescription foods. In our study, it was aimed to determine the levels of some elements and minerals in various prescription and non-prescription dry foods used in dog nutrition and to evaluate their therapeutic importance. In the study, a total of 100 different prescription dry food formulated for hepatic diseases (H, n=25), renal diseases (R, n=25), gastrointestinal diseases (GI, n=25) and, allergic diseases (HA, n=25) were used. Non-prescription dry foods from different flavors and brands in the market were considered as the control group (C, n=50). Copper (Cu), Iron (Fe), Manganese (Mn), Zinc (Zn), Selenium (Se), Calcium (Ca), and Phosphorus (P) levels of all dry foods were analyzed by Inductively Coupled Plasma -Optical Emission Spectrometer (ICP-OES, Thermo iCAP 6000 series) and the results were compared between groups. Statistical analysis was evaluated using SPSS 21. Cu levels in GI and HA groups were higher than in the control group (p<0.05 and p<0.01, respectively). Fe levels were higher in the GI group and lower in the HA group than in the control group (p<0.05). Mn level was significantly higher in the H group compared to the control group (p<0.001). The Mn levels in GI and HA groups were higher than the control group (p<0.01). There was no statistical difference in Se and Zn levels between prescription and non-prescription dry foods. Ca and P levels in all groups were statistically lower than in the control group (p<0.001). There are significant differences in element and mineral levels in prescription and nonprescription dry foods. These values may be out of the legal limits determined by EU Regulation. Considering the therapeutic purpose of these prescription formulas, some element and mineral amounts were determined as inappropriate.
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    Sistemik Aspergillosis Ve Kandidiyazisin Tedavisinde Ekinokandin Grubu Antimikotiklerin Etkinliği Ve Veteriner Hekimliğindeki Yeri
    (Journal of Advances in VetBio Science and Techniques, 2018) Ates Alkan, Fatma; Nasiboglu, Belgi; Dokuzeylul, Banu; Barutcu, Umit Bora; Or, Mehmet Erman
    İnsan ve hayvan sağlığı açısından fungal hastalıklar büyük sorun yaratmaktadır. Bu nedenle son kırk yılda pek çok antifungal üretilmiş ve sağlık alanında kullanıma başlanmıştır. İlaçların kullanımı ile birlikte dirençli mantar etkenlerinin ortaya çıkması sık kullanılan antimikotiklerin yerine alternatif ilaçların üretilmesini zorunlu kılmıştır. Bu derlemede, sistemik mikozlardan Candida spp. ve Aspergillus spp. tedavisinde uzun süredir kullanılan, polien ve azol grubu antifungallere alternatif olarak; veteriner hekimlikte ekinokandin grubu ilaçların kullanımının arttırılması yönünde bilinç uyandırmak amaçlanmıştır.
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    Use of Hair as Matrix for Trace Elements Biomonitoring in Cattle and Roe Deer Sharing Pastures in Northern Italy
    (MDPI, 2024) Draghi, Susanna; Fehri, Nour Elhouda; Ates, Fatma; Ozsobaci, Nural Pastaci; Tarhan, Duygu; Bilgic, Bengu; Dokuzeylul, Banu
    Simple Summary This study investigates using hair analysis to monitor potentially toxic elements (PTEs) in cattle and roe deer sharing pastures in Northern Italy. PTEs include essential and non-essential elements that, if unbalanced in organisms, can lead to health issues. Hair analysis is a non-invasive method that allows retrospective evaluation of PTE exposure. Aluminum, As, Cd, Cr, Ni, Pb, Cu, Mg, Fe, and Zn were measured. Findings indicate significantly higher As levels in roe deer due to selective feeding, while Cd and Pb levels align with other studies. Cattle have lower Cu, Fe, and Zn levels, likely due to dietary differences. Elevated Cr and Ni in cattle suggest contamination or physiological differences. Hair analysis proves valuable for monitoring environmental PTE exposure, emphasizing interspecies differences and the potential of both animals as bioindicators.Abstract Intensive cattle breeding's environmental challenges are prompting shifts to extensive, pasture-based systems, influencing nutrient and pollutant uptake. PTEs are essential and non-essential elements, regularly found in the environment and organisms, and in which unbalances lead to health issues. Hair analysis, a non-invasive method, provides retrospective PTE exposure evaluation. This study aims to understand exposure and species-specific accumulation patterns of PTEs in cattle and roe deer sharing pastures in Northern Italy using the hair analysis. Aluminum, As, Cd, Cr, Ni, Pb, Cu, Mg, Fe, and Zn were quantified through the use of ICP-OES. Findings show As levels significantly higher in roe deer due to their selective feeding, while Cd and Pb levels align with other studies. Essential elements like Cu, Fe, and Zn are lower in cattle, possibly due to diet differences. Higher Cr and Ni levels in cattle suggest contamination or physiological differences in accumulation patterns. In conclusion, hair analysis is valuable for monitoring environmental PTE exposure, highlighting significant interspecies differences and the potential of both animals as bioindicators in shared grazing areas.