Analysis of atherosclerosis by inductively coupled plasma optical emission spectroscopy and scanning acoustic microscopy

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dc.contributor.authorTanoren, Bukem
dc.contributor.authorUgurlucan, Murat
dc.contributor.authorAlkan, Fatma Ates
dc.date.accessioned2024-03-13T10:35:32Z
dc.date.available2024-03-13T10:35:32Z
dc.date.issued2020
dc.departmentİstanbul Beykent Üniversitesien_US
dc.description.abstractCalcium deposition within the atherosclerotic plaques is the precursor of cardiovascular complications. Therefore, determination of levels of minerals and trace elements in blood plays an important role in assigning the stage of atherosclerosis. In this study, determination of mineral and trace element levels in atherosclerotic patients is aimed. Mineral and trace element levels within serum samples of 12 atherosclerotic patients were evaluated by Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) and phosphorous (P), iron (Fe), magnesium (Mg) and calcium (Ca) levels were examined. Human carotid atherosclerotic plaque samples were previously screened by Scanning Acoustic Microscopy (SAM) and sound speed maps of the plaques showed higher sound speed values in the calcified regions, when compared to collagen-rich regions, indicating accumulation of calcium. Element analysis also showed increased Ca levels within serum samples. Therefore, it can be concluded that Ca deposition can be examined by ICP-OES and SAM, indicating that these techniques are confirmatory and may be combined to characterize atherosclerosis in the future.en_US
dc.description.sponsorshipMinistry of Development of Turkey [2009K120520]en_US
dc.description.sponsorshipScanning acoustic microscopy studies were funded by the Ministry of Development of Turkey [grant number 2009K120520].en_US
dc.identifier.doi10.1088/2057-1976/ab8e96
dc.identifier.issn2057-1976
dc.identifier.issue4en_US
dc.identifier.pmid33444265en_US
dc.identifier.scopus2-s2.0-85085546458en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1088/2057-1976/ab8e96
dc.identifier.urihttps://hdl.handle.net/20.500.12662/4471
dc.identifier.volume6en_US
dc.identifier.wosWOS:000536023300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIop Publishing Ltden_US
dc.relation.ispartofBiomedical Physics & Engineering Expressen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectatherosclerosisen_US
dc.subjectscanning acoustic microscopyen_US
dc.subjectinductively coupled plasma optical emission spectrometryen_US
dc.titleAnalysis of atherosclerosis by inductively coupled plasma optical emission spectroscopy and scanning acoustic microscopyen_US
dc.typeArticleen_US

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