Polat, NedimBozkurt, GulpembeCelebi, Irfan2019-03-282019-03-2820181471-2342https://doi.org/10.1186/s12880-018-0261-9Background: Malignant plasma cell proliferation may present as a disseminated disease (multiple myeloma), a solitary plasmacytoma of bone, or an extramedullary plasmacytoma of soft tissue. The latter plasmacytomas represent approximately 3% of all plasma cell proliferations, and 80% develop in the head-and-neck region. The unexpected clinical presentation of such masses may be present. Case presentation: Here, we report a rare case of primary tonsillar plasmacytoma in a 42-year-old female. The patient presented with asymmetric tonsillar hypertrophy that was resistant to antibiotherapy. Upon further workup, we found no evidence of multiple myeloma or light-chain disease. The patient underwent surgery and, at the last followup, exhibited no evidence of such disease. Conclusions: In adults presenting with asymptomatic tonsillar enlargement, the possibility of submucosal masses should be considered, thus encouraging the radiologist to evaluate crypts within the palatine tonsil on a postcontrast MRI, besides enlargement and signal change.enPlasmacytomaMultiple myelomaMagnetic resonance imagingAsymmetric tonsillar enlargementArticle10.1186/s12880-018-0261-92-s2.0-8504870175029914385Q2WOS:000435881000001Q2