Aynacı, EnginKarakurt, Gökhan2025-03-092025-03-0920232547-9431https://doi.org/10.4274/BMB.galenos.2023.2023-01-01https://search.trdizin.gov.tr/tr/yayin/detay/1254954https://hdl.handle.net/20.500.12662/4792Objective: In our study, we aimed to investigate the long-term effects of the acute phase parameters of C-reactive protein, procalcitonin, D-dimer, lymphocyte, thrombocyte and ferritin on the respiratory function parameters in patients hospitalized due to Coronavirus disease-2019 (COVID-19) pneumonia. Method: The present study was carried out with the retrospective evaluation of patients with COVID-19 pneumonia, who were hospitalized in Medipol University Hospital between March 2020 and June 2021, and who were 6 months to 1 year after discharge. The relationship between pulmonary function test results and acute period laboratory findings of 52 patients who applied for control purposes 6 months after discharge was examined. Results: Diffusing capacity for carbon monoxide (DLCO) (pred) value in 26 patients (50%), total lung capacity (TLC) value in 9 patients (17.3%), and residual volume (RV) (pred) value in 10 patients (19.2%) were below 80%. As a result of multiple linear regression analysis in our study, the maximum D-dimer level and maximum procalcitonin level were determined by DLCO (% pred) (adjusted R 2 =0.645; p<0.001), TLC (% pred) (adjusted R2 =0.582; p=0.003) and RV (% pred) (adjusted R2 =0.560; p=0.001) values and were independent determinants in predicting these values. Conclusion: High D-dimer and procalcitonin levels in the acute period in patients with COVID-19 pneumonia may predict losses in respiratory function parameters such as DLCO, TLC, RV in the longer term than 6 months. Long-term follow-up of these patients is important in terms of respiratory function.eninfo:eu-repo/semantics/openAccessCOVID-19D-dimerDLCOArticle10.4274/BMB.galenos.2023.2023-01-01215321012549548